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Vol. 35. Issue 1.
Pages 32-40 (January 2011)
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Vol. 35. Issue 1.
Pages 32-40 (January 2011)
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Anemia and transfusion therapy: an update
Actualización en anemia y terapia transfusional
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Z. Madrazo-Gonzáleza,c,
Corresponding author
zoiluco@yahoo.es

Corresponding author.
, A. García-Barrasaa,c, L. Rodríguez-Lorenzob,c, A. Rafecas-Renaua, G. Alonso-Fernándezd
a Servicio de Cirugía General yA parato Digestivo, Hospital Universitario de Bellvitge, Barcelona, Spain
b Servicio de Angiología y Cirugía Vascular, Hospital Universitario de Bellvitge, Barcelona, Spain
c Member of the AWGE (Anemia Working Group), Grupo multidisciplinar para el estudio y manejo clínico de la anemia del paciente quirúrgico (AWGE.ORG), Spain
d Servicio de Urgencias, Hospital Universitario de Bellvitge, Barcelona, Spain
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Abstract

Anemia is one of the most prevalent diseases in the general population and is a very frequently found condition in medical and surgical patients in all medical specialties. A good evaluation of its clinical impact and its therapeutic possibilities is essential. Allogenic blood transfusion is a useful procedure in anemia management, although it has important adverse effects. It is the responsibility of the clinician to know and to take into account all the available alternatives for the treatment of anemia. Blood transfusions, erythropoiesis-stimulating agents, iron therapy (oral and endovenous) and other therapeutic alternatives must be rationally used, in accordance with the currently available clinical evidence. This review article summarizes some epidemiological characteristics of anemia, its clinical evaluation and the main therapeutic possibilities based on the present knowledge, placing special emphasis on the critically ill patient.

Keywords:
Anemia
Transfusion
Iron Therapy
Resumen

La anemia representa una de las patologías más prevalentes en la población general y constituye una entidad extremadamente frecuente en pacientes médicos y quirúrgicos de todas las especialidades. Una correcta valoración de su impacto y de las posibilidades terapéuticas resulta crucial. La transfusión de sangre alogénica representa una medida eficaz en el manejo de la anemia, pero no está exenta de importantes complicaciones. Es responsabilidad del clínico conocer y sopesar todas las alternativas disponibles para el manejo global de la anemia. Transfusiones sanguíneas, agentes estimuladores de la eritropoyesis, ferroterapia (oral y endovenosa) y otras alternativas terapéuticas han de ser empleadas de forma racional y ajustándonos a la evidencia clínica disponible hasta la fecha. El presente artículo de revisión resume algunas características epidemiológicas de la anemia, su valoración clínica y las principales alternativas terapéuticas a la luz de los conocimientos actuales, con especial énfasis en el paciente crítico.

Palabras clave:
Anemia
Transfusión
Ferroterapia
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