TY - JOUR T1 - Pressure versus volume controlled modes in invasive mechanical ventilation JO - Medicina Intensiva (English Edition) T2 - AU - Garnero,A.J. AU - Abbona,H. AU - Gordo-Vidal,F. AU - Hermosa-Gelbard,C. SN - 21735727 M3 - 10.1016/j.medine.2012.10.015 DO - 10.1016/j.medine.2012.10.015 UR - https://medintensiva.org/en-pressure-versus-volume-controlled-modes-articulo-S2173572713000404 AB - The first generation of mechanical ventilators were controlled and cycled by pressure. Unfortunately, they did not allow control of the delivered tidal volume under changes in the dynamics of the respiratory system. This led to a second generation of ventilators that allowed volume control, hence favoring the ventilatory strategy based on normalization of the arterial gases.Studies conducted in the 1980s which related lung injury to the high ventilator pressures utilized while treating acute respiratory distress syndrome patients renewed interest in pressure-controlled mechanical ventilation. In addition, new evidence became available, leading to the development of pulmonary protective strategies aiming at preventing the progression of ventilator-induced lung injury.This review provides a detailed description of the control of pressure or volume using certain ventilatory modes, and offers a general view of their advantages and disadvantages, based on the latest available evidence. ER -