CommentNutritional support and refeeding syndrome in critical illness
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Cited by (25)
An unexpectedly high incidence of refeeding syndrome in patients with total parenteral nutrition in a reference university hospital
2021, Clinical NutritionCitation Excerpt :RFS and its association with clinical outcomes is controversial. Some studies correlate this condition with a high risk of morbidity and mortality [5–7], complications such as electrolyte, cardiac and pulmonary disorders [8] and longer hospital stays [6,9], while others have found no association between patients with refeeding syndrome and longer periods of hospitalization [10], days on mechanical ventilation [11]and mortality [10,11]. The present study aimed to identify the incidence of refeeding syndrome in hospitalized patients using Total Parenteral Nutrition (TPN) and clinical and nutritional factors that may be associated with this condition, as well as nutritional management and clinical outcomes.
Incidence and outcome of refeeding syndrome in neurocritically ill patients
2021, Clinical NutritionCitation Excerpt :Refeeding syndrome (RFS) refers to the biochemical and clinical symptoms and metabolic abnormalities in malnourished patients undergoing refeeding, whether induced by oral, enteral, or parenteral feeding [1]. The RFS syndrome is usually characterized by low serum concentrations of predominately intracellular ions such as phosphate, magnesium, and potassium, but abnormalities in the metabolism of glucose, thiamine, and levels of sodium and water balance have been frequently noted [1]. These biochemical abnormalities could cause consequential metabolic disturbances to the cardiac, respiratory, hepatic, hematological, and neuromuscular systems and ultimately lead to multiple organ dysfunction and death [2].
Refeeding risks in patients requiring intravenous nutrition support: Results of a two-centre, prospective, double-blind, randomised controlled trial
2021, Clinical Nutrition ESPENCitation Excerpt :In patients receiving enteral nutrition at a level insufficient to meet demands, later initiation of supplemental parenteral nutrition is associated with faster recovery and fewer complications [25] suggesting that early caloric restriction, particularly in the critically ill is of benefit. A subsequent randomised controlled trial demonstrated the caloric restriction to 20 kcal/h, in patients who developed hypophosphataemia and another sign of refeeding syndrome within 72 h of commencing nutritional support, was associated with a reduction in mortality rates and major infections [26,27]. Additionally, in another study 36.8% of critically ill, mechanically ventilated patients developed hypophosphataemia and those fed at 50% target rate had improved 6 month outcomes [28].
When and how should I feed the critically ill patient?
2019, Evidence-Based Practice of Critical CareThe refeeding syndrome
2016, Medecine des Maladies Metaboliques