CardiomyopathyNationwide Trends in Reported Incidence of Takotsubo Cardiomyopathy from 2006 to 2012
Section snippets
Methods
Data were obtained from the Nationwide (now renamed National) Inpatient Sample (NIS), created by the Agency for Healthcare Research and Quality.14 The NIS is the largest publicly available all-payer inpatient health care database in the United States. We obtained data for each year from 2006 to 2012. Before 2012, the NIS database drew from 100% of hospital discharges from approximately 1,000 hospitals. Beginning in 2012, the database represents a 20% sample of discharges from all community
Results
The reported incidence of TC increased significantly over the study period, with 315 cases in 2006 and 6,230 cases in 2012 (p <0.001 for trend; Table 1, Figure 1). Median length of hospital stay was stable over the study period (3.4 days in 2006 vs 3.6 days in 2012; p = 0.74 for trend). Inhospital death rate remained <2%. Data was only available for 2011 and 2012 for this category.
The diagnosis was most frequent in the subjects aged 65 to 84 years (47% to 55% of cases), followed by those
Discussion
TC was initially described in Japan in 1991 in a case series of 5 patients.16 Since then, several studies have examined the incidence of TC in patients presenting with ACS.1, 2, 7, 8, 9 However, to date, few studies have reported on its overall incidence, particularly in the United States. We found that the reported incidence of TC has significantly increased from 2006 to 2012, with an incidence that is >19 times higher in 2012 compared to 2006. This is most likely due to the increasing
Disclosures
The authors have no conflicts of interest to disclose.
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