Coma metabólico secundario a sertralina
Sertraline-Induced Metabolic Coma
J. López1
, M. Casares, G. Soriano, A. Madero, M.T. Jurado, R. Jordà
Autor para correspondencia
Lopezlibano@hotmail.com
Correspondencia: Dr. J. López. C/ Moragues, 7, 2.º 1.ª. 07006 Palma de Mallorca
Correspondencia: Dr. J. López. C/ Moragues, 7, 2.º 1.ª. 07006 Palma de Mallorca
Unidad de Cuidados Intensivos. Hospital Son Dureta. Mallorca
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Jordà" "autores" => array:6 [ 0 => array:4 [ "nombre" => "J." "apellidos" => "López" "email" => array:1 [ 0 => "Lopezlibano@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Casares" ] 2 => array:2 [ "nombre" => "G." "apellidos" => "Soriano" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Madero" ] 4 => array:2 [ "nombre" => "M.T." "apellidos" => "Jurado" ] 5 => array:2 [ "nombre" => "R." "apellidos" => "Jordà" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Unidad de Cuidados Intensivos. Hospital Son Dureta. Mallorca" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Dr. J. López. C/ Moragues, 7, 2.º 1.ª. 07006 Palma de Mallorca" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Sertraline-Induced Metabolic Coma" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2000-10-13" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec82383" "palabras" => array:3 [ 0 => "sertralina" 1 => "SSIADH" 2 => "coma" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec82384" "palabras" => array:3 [ 0 => "sertraline" 1 => "syndrome of inappropriate secretion of antidiuretic hormone" 2 => "coma" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La sertralina es un fármaco inhibidor de la recaptación de serotonina en el sistema nervioso central que se utiliza como antidepresivo. Entre sus efectos secundarios se ha descrito la presentación de síndrome de secreción inadecuada de ADH, especialmente en individuos de edad avanzada. En la mayoría de los pacientes afectados, los síntomas revistieron escasa gravedad y pudieron ser rápidamente revertidos.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Presentamos los casos de 2 mujeres de mediana edad que desarrollaron SSIADH e hiponatremia severa después de haber seguido tratamiento con sertralina. Ambas ingresaron en nuestra unidad de cuidados intensivos en estado de coma inferior o igual a 8 puntos en la escala de Glasgow y necesitaron ventilación mecánica invasiva.</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Sertraline selectively inhibits the reuptake of serotonin in the central nervous system and is used as an antidepressant drug. The syndrome of inappropriate secretion of antidiuretic hormone (SIADH), especially in the elderly, has been described as one of its adverse affects. In most patients, symptoms were mild and soon disappeared.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We present the cases of two middle-aged women who developed SIADH and severe hyponatremia after sertraline treatment. Both were admitted to our intensive care unit in a state of coma lower or equal to 8 points in the Glasgow Coma Scale and required invasive mechanical ventilation.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:12 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| 2017 Marzo | 19 | 36 | 55 |
| 2017 Febrero | 13 | 26 | 39 |
| 2017 Enero | 13 | 15 | 28 |
| 2016 Diciembre | 14 | 24 | 38 |
| 2016 Noviembre | 20 | 20 | 40 |
| 2016 Octubre | 33 | 56 | 89 |
| 2016 Septiembre | 50 | 68 | 118 |
| 2016 Agosto | 51 | 50 | 101 |
| 2016 Julio | 29 | 36 | 65 |
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