Role of viral infections in immunosuppressed patients
Papel de las infecciones víricas en pacientes inmunodeprimidos
a Unidad de Enfermedades Infecciosas, Hospital Universitario y Politécnico La Fe, Valencia, Spain
b Servicio de Medicina Intensiva, Hospital Universitario de Bellvitge, l’Hospitalet de Llobregat, Barcelona, Spain
c Servicio de Medicina Intensiva, Hospital Universitario Virgen del Rocío, Sevilla, Spain
d Servicio de Medicina Intensiva, Hospital Universitario Dr. Peset, Valencia, Spain
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The patient may have acquired these infections from the community as well as from the donor organ (donor-derived infections) and/or from reactivation of an endogenous latent virus. Herpes viruses and especially the cytomegalovirus and Epstein-Barr virus are among the most common of the opportunistic viral pathogens affecting these patients, in addition to respiratory viruses. Treatment consists in antiviral drug therapies combined with the reduction in the degree of the induced immunosuppression. A review of the literature has been performed in order to update the epidemiology, pathogenesis, clinical manifestations and therapeutic approach of the viral infections in these immunocompromised patients.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Ser receptor de un trasplante de órgano sólido, así como recibir tratamiento quimioterápico para una enfermedad hematológica maligna, predispone claramente a padecer infecciones virales tanto comunes como oportunistas, de origen tanto comunitario como procedentes del donante de órganos y/o de una reactivación de un virus latente endógeno. Herpes virus y más especialmente citomegalovirus y virus de Epstein-Barr son los que con más frecuencia afectan a estos enfermos, así como los virus respiratorios. El tratamiento consiste en la combinación de reducir la inmunodepresión inducida junto con tratamiento antiviral. Se ha realizado una revisión de la literatura pormenorizada y actualizada de la epidemiología, la patogenia, las manifestaciones clínicas y la aproximación terapéutica de las infecciones virales en estos enfermos.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:46 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Approach to the immunocompromised host with infection in the intensive care unit" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.K. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 12 | 16 |
| 2024 October | 41 | 72 | 113 |
| 2024 September | 35 | 38 | 73 |
| 2024 August | 43 | 55 | 98 |
| 2024 July | 33 | 39 | 72 |
| 2024 June | 34 | 27 | 61 |
| 2024 May | 29 | 28 | 57 |
| 2024 April | 40 | 46 | 86 |
| 2024 March | 35 | 21 | 56 |
| 2024 February | 34 | 48 | 82 |
| 2024 January | 31 | 53 | 84 |
| 2023 December | 27 | 49 | 76 |
| 2023 November | 18 | 27 | 45 |
| 2023 October | 33 | 102 | 135 |
| 2023 September | 25 | 30 | 55 |
| 2023 August | 17 | 20 | 37 |
| 2023 July | 20 | 38 | 58 |
| 2023 June | 20 | 17 | 37 |
| 2023 May | 8 | 10 | 18 |
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