array:23 [
  "pii" => "S2173572713000532"
  "issn" => "21735727"
  "doi" => "10.1016/j.medine.2012.04.008"
  "estado" => "S300"
  "fechaPublicacion" => "2013-05-01"
  "aid" => "466"
  "copyright" => "Elsevier España, S.L. and SEMICYUC"
  "copyrightAnyo" => "2012"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Med Intensiva. 2013;37:241-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2106
    "formatos" => array:3 [
      "EPUB" => 194
      "HTML" => 1035
      "PDF" => 877
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173572713000404"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2012.10.015"
    "estado" => "S300"
    "fechaPublicacion" => "2013-05-01"
    "aid" => "528"
    "copyright" => "Elsevier España, S.L. and SEMICYUC"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Med Intensiva. 2013;37:292-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 23434
      "formatos" => array:3 [
        "EPUB" => 194
        "HTML" => 20895
        "PDF" => 2345
      ]
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Update in intensive care&#58; transplants</span>"
      "titulo" => "Pressure versus volume controlled modes in invasive mechanical ventilation"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "292"
          "paginaFinal" => "298"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Modos controlados por presi&#243;n versus volumen en la ventilaci&#243;n mec&#225;nica invasiva"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46;J&#46; Garnero, H&#46; Abbona, F&#46; Gordo-Vidal, C&#46; Hermosa-Gelbard"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "A&#46;J&#46;"
              "apellidos" => "Garnero"
            ]
            1 => array:2 [
              "nombre" => "H&#46;"
              "apellidos" => "Abbona"
            ]
            2 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Gordo-Vidal"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Hermosa-Gelbard"
            ]
            4 => array:1 [
              "colaborador" => "in representation of the Acute Respiratory Failure Group of the SEMICYUC"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0210569112003166"
        "doi" => "10.1016/j.medin.2012.10.007"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569112003166?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572713000404?idApp=WMIE"
    "url" => "/21735727/0000003700000004/v1_201307160921/S2173572713000404/v1_201307160921/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173572713000374"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2012.07.009"
    "estado" => "S300"
    "fechaPublicacion" => "2013-05-01"
    "aid" => "505"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and SEMICYUC"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Med Intensiva. 2013;37:224-31"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2832
      "formatos" => array:3 [
        "EPUB" => 138
        "HTML" => 1842
        "PDF" => 852
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
      "titulo" => "Alpha code&#46; The start of a new non-heart beating donor program"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "224"
          "paginaFinal" => "231"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "C&#243;digo alfa&#46; Inicio de un nuevo programa de donaci&#243;n en asistolia"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1403
              "Ancho" => 2378
              "Tamanyo" => 141827
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Alpha Code&#46; Activation of the rapid response team&#46; &#42;Supervising nurse on duty&#58; nurse in charge of guaranteeing continuity in nursing management during the duty shift&#46; In the morning the ICU supervising nurse of Neurotraumatology participates in Alpha Code activation&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46;M&#46; P&#233;rez-Villares, R&#46; Lara-Rosales, F&#46; Pino-S&#225;nchez, P&#46; Fuentes-Garc&#237;a, E&#46; Gil-Pi&#241;ero, A&#46; Osuna Ortega, J&#46;M&#46; Cozar Olmo"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "J&#46;M&#46;"
              "apellidos" => "P&#233;rez-Villares"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Lara-Rosales"
            ]
            2 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Pino-S&#225;nchez"
            ]
            3 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Fuentes-Garc&#237;a"
            ]
            4 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Gil-Pi&#241;ero"
            ]
            5 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Osuna Ortega"
            ]
            6 => array:2 [
              "nombre" => "J&#46;M&#46;"
              "apellidos" => "Cozar Olmo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0210569112002471"
        "doi" => "10.1016/j.medin.2012.07.009"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569112002471?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572713000374?idApp=WMIE"
    "url" => "/21735727/0000003700000004/v1_201307160921/S2173572713000374/v1_201307160921/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
    "titulo" => "Differences in hospital- and ventilator-associated pneumonia due to Staphylococcus aureus &#40;methicillin-susceptible and methicillin-resistant&#41; between Europe and Latin America&#58; A comparison of the EUVAP and LATINVAP study cohorts"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "241"
        "paginaFinal" => "247"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "J&#46; Rello, D&#46; Molano, M&#46; Villabon, R&#46; Reina, R&#46; Rita-Quispe, I&#46; Previgliano, E&#46; Afonso, M&#46;I&#46; Restrepo"
        "autores" => array:8 [
          0 => array:4 [
            "nombre" => "J&#46;"
            "apellidos" => "Rello"
            "email" => array:1 [
              0 => "Jrello&#64;crips&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "D&#46;"
            "apellidos" => "Molano"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Villabon"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Reina"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Rita-Quispe"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "I&#46;"
            "apellidos" => "Previgliano"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "E&#46;"
            "apellidos" => "Afonso"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          7 => array:3 [
            "nombre" => "M&#46;I&#46;"
            "apellidos" => "Restrepo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">f</span>"
                "identificador" => "aff0030"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:6 [
          0 => array:3 [
            "entidad" => "Critical Care Department&#44; Vall d&#8217;Hebron University Hospital&#44; IRVH&#44; CIBERes&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Critical Care Department&#44; University Hospital of San Jos&#233;&#44; Fundaci&#243;n Universitaria de Ciencias de la Salud &#40;FUCS&#41;&#44; Bogot&#225;&#44; Colombia"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Critical Care Department&#44; Hospital Fernadez&#44; Capital Federal&#44; Argentina"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Critical Care Department&#44; Hospital San Martin de la Plata&#44; Argentina"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff0020"
          ]
          4 => array:3 [
            "entidad" => "Critical Care Department&#44; Hospital Nacional Dos de Mayo&#44; Lima&#44; Peru"
            "etiqueta" => "<span class="elsevierStyleSup">e</span>"
            "identificador" => "aff0025"
          ]
          5 => array:3 [
            "entidad" => "Veterans Evidence Research Dissemination and Implementation Center &#40;VERDICT&#41;&#44; Department of Medicine&#44; The University of Texas Health Science Center at San Antonio&#44; USA"
            "etiqueta" => "<span class="elsevierStyleSup">f</span>"
            "identificador" => "aff0030"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2012-02-13"
    "fechaAceptado" => "2012-04-24"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec208819"
          "palabras" => array:5 [
            0 => "Methicillin-resistant Staphylococcus aureus"
            1 => "Ventilator-associated pneumonia"
            2 => "Respiratory infections"
            3 => "Staphylococcus aureus"
            4 => "Pneumonia"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec208818"
          "palabras" => array:5 [
            0 => "SAMR"
            1 => "NAV"
            2 => "Infecciones respiratorias"
            3 => "Staphylococcus aureus"
            4 => "Neumon&#237;a"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle" id="sect0010">Purpose</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A comparison is made of epidemiological variables &#40;demographic and clinical characteristics&#41; and outcomes in patients with hospital-acquired pneumonia &#40;HAP&#41; or ventilator- associated pneumonia &#40;VAP&#41; caused by methicillin-susceptible and methicillin-resistant <span class="elsevierStyleItalic">Staphylococcus aureus</span> &#40;MSSA and MRSA&#41; in the Latin American VAP &#40;LATINVAP&#41; vs&#46; the European Union VAP &#40;EUVAP&#41; cohorts of patients admitted to intensive care units &#40;ICUs&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The EUVAP project was a prospective&#44; multicenter observational study reporting 827 patients with HAP&#47;VAP in 27 ICUs from 9 European countries&#46; The LATINVAP project was a multicenter prospective observational study&#44; with an identical design&#44; performed in 17 ICUs from 4 Latin American countries involving 99 patients who developed HAP&#47;VAP&#46; Episodes of VAP&#47;HAP caused by <span class="elsevierStyleItalic">S&#46; aureus</span>&#44; MSSA&#44; and MRSA were compared in both cohorts&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Forty-&#64257;ve patients had <span class="elsevierStyleItalic">S&#46; aureus</span> HAP&#47;VAP in the EUVAP cohort vs&#46; 11 patients in the LATINVAP cohort&#46; More patients had MRSA in the LATINVAP study than in the EUVAP &#40;45&#37; vs&#46; 33&#37;&#41;&#46; ICU mortality among patients with MSSA HAP&#47;VAP in EUVAP was 10&#37; vs&#46; 50&#37; for LATINVAP &#40;OR &#61; 9&#46;75&#44; <span class="elsevierStyleItalic">p</span> &#61; 0&#46;01&#41;&#46; Fifteen patients in the EUVAP cohort developed MRSA HAP&#47;VAP as opposed to 5 in LATINVAP&#46; In the EUVAP study there was an ICU mortality rate of 33&#46;3&#37;&#46; In the LATINVAP cohort&#44; the ICU mortality rate was 60&#37; &#40;OR for death &#61; 3&#46;0&#59; 95&#37;CI 0&#46;24---44&#46;7&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">MRSA pneumonia was associated with poorer outcomes in comparison with MSSA&#46; Our study suggests signi&#64257;cant variability among European and Latin American ICU practices that may in&#64258;uence clinical outcomes&#46; Furthermore&#44; patients with pneumonia in Latin America have different outcomes&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">comparar las variables epidemiol&#243;gicas &#40;caracter&#237;sticas demogr&#225;&#64257;cas y cl&#237;nicas&#41; y los efectos en pacientes con neumon&#237;a intrahospitalaria &#40;NIH&#41; o neumon&#237;a asociada a la ventilaci&#243;n &#40;NAV&#41; causada por <span class="elsevierStyleItalic">Staphylococcus aureus</span> susceptible a la meticilina &#40;SASM&#41; y resistente a la meticilina &#40;SARM&#41; en las cohortes LATINVAP y EUVAP de pacientes admitidos en unidades de cuidados intensivos &#40;UCI&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El proyecto EUVAP fue un estudio prospectivo&#44; multic&#233;ntrico y observacional sobre 827 pacientes con NIH&#47;NAV de 27 UCI de 9 pa&#237;ses europeos&#46; El proyecto LATINVAP fue un estudio pospectivo&#44; multic&#233;ntrico y observacional de id&#233;ntico disen¿o que se llev&#243; a cabo en 17 UCI de 4 pa&#237;ses latinoamericanos y en el que se evaluaron 99 pacientes que hab&#237;an desarrollado HAP&#47;VAP&#46; Se compararon entre las cohortes los episodios de VAP&#47;HAP causados por <span class="elsevierStyleItalic">S&#46; aureus</span> &#40;SASM y SARM&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cuarenta y cinco pacientes presentaron NIH&#47;NAV por <span class="elsevierStyleItalic">S&#46; aureus</span> en la cohorte EUVAP frente a 11 pacientes en la cohorte LATINVAP&#46; El n&#250;mero de pacientes con SARM en el estudio LATINVAP fue superior al del estudio EUVAP &#40;45&#37; frente al 33&#37;&#41;&#46; La mortalidad en la UCI entre los pacientes con NIH&#47;NAV por SASM del estudio EUVAP fue del 10&#37; frente al 50&#37; en el caso del estudio LATINVAP &#40;OR &#61; 9&#44;75&#44; p &#61; 0&#44;01&#41;&#46; Quince pacientes de la cohorte EUVAP desarrollaron NIH&#47;NAV por SARM frente a 5 de la cohorte LATINVAP&#46; En el estudio EUVAP se registr&#243; una tasa de mortalidad del 33&#44;3&#37;&#46; En la cohorte LATINVAP la tasa de mortalidad en la UCI fue del 60&#37; &#40;OR de muerte &#61; 3&#44;0&#59; IC del 95&#37; de 0&#44;24 a 44&#44;7&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La neumon&#237;a por SARM se asoci&#243; a unos peores resultados en comparaci&#243;n con la neumon&#237;a por SASM&#46; Nuestro estudio sugiere una variabilidad importante entre las pr&#225;cticas de las UCI europeas y latinoamericanas que podr&#237;a in&#64258;uir sobre los resulta- dos cl&#237;nicos&#46; Adem&#225;s&#44; los pacientes con neumon&#237;a de Latinoam&#233;rica presentaron resultados diferentes&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Rello J&#46;&#44; et al&#46; Diferencias entre la neumon&#237;a de origen nosocomial y asociada a la ventilaci&#243;n por <span class="elsevierStyleItalic">Staphylococcus aureus</span> &#40;susceptible a la meticilina y resistente a la meticilina&#41; en europa y latinoam&#233;rica&#58; comparaci&#243;n de las cohortes de estudio EUVAP y LATINVAP&#46; Med Intensiva&#46; 2012&#46; http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;j&#46;medine&#46;2012&#46;04&#46;008&#46;</p>"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735727/0000003700000004/v1_201307160921/S2173572713000532/v1_201307160921/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "411"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735727/0000003700000004/v1_201307160921/S2173572713000532/v1_201307160921/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572713000532?idApp=WMIE"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Original
Differences in hospital- and ventilator-associated pneumonia due to Staphylococcus aureus (methicillin-susceptible and methicillin-resistant) between Europe and Latin America: A comparison of the EUVAP and LATINVAP study cohorts
J. Relloa,
Corresponding author
Jrello@crips.es

Corresponding author.
, D. Molanob, M. Villabonb, R. Reinad, R. Rita-Quispee, I. Previglianoc, E. Afonsoa, M.I. Restrepof
a Critical Care Department, Vall d’Hebron University Hospital, IRVH, CIBERes, Barcelona, Spain
b Critical Care Department, University Hospital of San José, Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia
c Critical Care Department, Hospital Fernadez, Capital Federal, Argentina
d Critical Care Department, Hospital San Martin de la Plata, Argentina
e Critical Care Department, Hospital Nacional Dos de Mayo, Lima, Peru
f Veterans Evidence Research Dissemination and Implementation Center (VERDICT), Department of Medicine, The University of Texas Health Science Center at San Antonio, USA
Read
6023
Times
was read the article
3398
Total PDF
2625
Total HTML
Share statistics
 array:23 [
  "pii" => "S2173572713000532"
  "issn" => "21735727"
  "doi" => "10.1016/j.medine.2012.04.008"
  "estado" => "S300"
  "fechaPublicacion" => "2013-05-01"
  "aid" => "466"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and SEMICYUC"
  "copyrightAnyo" => "2012"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Med Intensiva. 2013;37:241-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2106
    "formatos" => array:3 [
      "EPUB" => 194
      "HTML" => 1035
      "PDF" => 877
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173572713000404"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2012.10.015"
    "estado" => "S300"
    "fechaPublicacion" => "2013-05-01"
    "aid" => "528"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and SEMICYUC"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Med Intensiva. 2013;37:292-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 23434
      "formatos" => array:3 [
        "EPUB" => 194
        "HTML" => 20895
        "PDF" => 2345
      ]
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Update in intensive care&#58; transplants</span>"
      "titulo" => "Pressure versus volume controlled modes in invasive mechanical ventilation"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "292"
          "paginaFinal" => "298"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Modos controlados por presi&#243;n versus volumen en la ventilaci&#243;n mec&#225;nica invasiva"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46;J&#46; Garnero, H&#46; Abbona, F&#46; Gordo-Vidal, C&#46; Hermosa-Gelbard"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "A&#46;J&#46;"
              "apellidos" => "Garnero"
            ]
            1 => array:2 [
              "nombre" => "H&#46;"
              "apellidos" => "Abbona"
            ]
            2 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Gordo-Vidal"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Hermosa-Gelbard"
            ]
            4 => array:1 [
              "colaborador" => "in representation of the Acute Respiratory Failure Group of the SEMICYUC"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0210569112003166"
        "doi" => "10.1016/j.medin.2012.10.007"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569112003166?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572713000404?idApp=WMIE"
    "url" => "/21735727/0000003700000004/v1_201307160921/S2173572713000404/v1_201307160921/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173572713000374"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2012.07.009"
    "estado" => "S300"
    "fechaPublicacion" => "2013-05-01"
    "aid" => "505"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and SEMICYUC"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Med Intensiva. 2013;37:224-31"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2832
      "formatos" => array:3 [
        "EPUB" => 138
        "HTML" => 1842
        "PDF" => 852
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
      "titulo" => "Alpha code&#46; The start of a new non-heart beating donor program"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "224"
          "paginaFinal" => "231"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "C&#243;digo alfa&#46; Inicio de un nuevo programa de donaci&#243;n en asistolia"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1403
              "Ancho" => 2378
              "Tamanyo" => 141827
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Alpha Code&#46; Activation of the rapid response team&#46; &#42;Supervising nurse on duty&#58; nurse in charge of guaranteeing continuity in nursing management during the duty shift&#46; In the morning the ICU supervising nurse of Neurotraumatology participates in Alpha Code activation&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46;M&#46; P&#233;rez-Villares, R&#46; Lara-Rosales, F&#46; Pino-S&#225;nchez, P&#46; Fuentes-Garc&#237;a, E&#46; Gil-Pi&#241;ero, A&#46; Osuna Ortega, J&#46;M&#46; Cozar Olmo"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "J&#46;M&#46;"
              "apellidos" => "P&#233;rez-Villares"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Lara-Rosales"
            ]
            2 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Pino-S&#225;nchez"
            ]
            3 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Fuentes-Garc&#237;a"
            ]
            4 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Gil-Pi&#241;ero"
            ]
            5 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Osuna Ortega"
            ]
            6 => array:2 [
              "nombre" => "J&#46;M&#46;"
              "apellidos" => "Cozar Olmo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0210569112002471"
        "doi" => "10.1016/j.medin.2012.07.009"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569112002471?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572713000374?idApp=WMIE"
    "url" => "/21735727/0000003700000004/v1_201307160921/S2173572713000374/v1_201307160921/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
    "titulo" => "Differences in hospital- and ventilator-associated pneumonia due to Staphylococcus aureus &#40;methicillin-susceptible and methicillin-resistant&#41; between Europe and Latin America&#58; A comparison of the EUVAP and LATINVAP study cohorts"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "241"
        "paginaFinal" => "247"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "J&#46; Rello, D&#46; Molano, M&#46; Villabon, R&#46; Reina, R&#46; Rita-Quispe, I&#46; Previgliano, E&#46; Afonso, M&#46;I&#46; Restrepo"
        "autores" => array:8 [
          0 => array:4 [
            "nombre" => "J&#46;"
            "apellidos" => "Rello"
            "email" => array:1 [
              0 => "Jrello&#64;crips&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "D&#46;"
            "apellidos" => "Molano"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Villabon"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Reina"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Rita-Quispe"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "I&#46;"
            "apellidos" => "Previgliano"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "E&#46;"
            "apellidos" => "Afonso"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          7 => array:3 [
            "nombre" => "M&#46;I&#46;"
            "apellidos" => "Restrepo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">f</span>"
                "identificador" => "aff0030"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:6 [
          0 => array:3 [
            "entidad" => "Critical Care Department&#44; Vall d&#8217;Hebron University Hospital&#44; IRVH&#44; CIBERes&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Critical Care Department&#44; University Hospital of San Jos&#233;&#44; Fundaci&#243;n Universitaria de Ciencias de la Salud &#40;FUCS&#41;&#44; Bogot&#225;&#44; Colombia"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Critical Care Department&#44; Hospital Fernadez&#44; Capital Federal&#44; Argentina"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Critical Care Department&#44; Hospital San Martin de la Plata&#44; Argentina"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff0020"
          ]
          4 => array:3 [
            "entidad" => "Critical Care Department&#44; Hospital Nacional Dos de Mayo&#44; Lima&#44; Peru"
            "etiqueta" => "<span class="elsevierStyleSup">e</span>"
            "identificador" => "aff0025"
          ]
          5 => array:3 [
            "entidad" => "Veterans Evidence Research Dissemination and Implementation Center &#40;VERDICT&#41;&#44; Department of Medicine&#44; The University of Texas Health Science Center at San Antonio&#44; USA"
            "etiqueta" => "<span class="elsevierStyleSup">f</span>"
            "identificador" => "aff0030"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2012-02-13"
    "fechaAceptado" => "2012-04-24"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec208819"
          "palabras" => array:5 [
            0 => "Methicillin-resistant Staphylococcus aureus"
            1 => "Ventilator-associated pneumonia"
            2 => "Respiratory infections"
            3 => "Staphylococcus aureus"
            4 => "Pneumonia"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec208818"
          "palabras" => array:5 [
            0 => "SAMR"
            1 => "NAV"
            2 => "Infecciones respiratorias"
            3 => "Staphylococcus aureus"
            4 => "Neumon&#237;a"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle" id="sect0010">Purpose</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A comparison is made of epidemiological variables &#40;demographic and clinical characteristics&#41; and outcomes in patients with hospital-acquired pneumonia &#40;HAP&#41; or ventilator- associated pneumonia &#40;VAP&#41; caused by methicillin-susceptible and methicillin-resistant <span class="elsevierStyleItalic">Staphylococcus aureus</span> &#40;MSSA and MRSA&#41; in the Latin American VAP &#40;LATINVAP&#41; vs&#46; the European Union VAP &#40;EUVAP&#41; cohorts of patients admitted to intensive care units &#40;ICUs&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The EUVAP project was a prospective&#44; multicenter observational study reporting 827 patients with HAP&#47;VAP in 27 ICUs from 9 European countries&#46; The LATINVAP project was a multicenter prospective observational study&#44; with an identical design&#44; performed in 17 ICUs from 4 Latin American countries involving 99 patients who developed HAP&#47;VAP&#46; Episodes of VAP&#47;HAP caused by <span class="elsevierStyleItalic">S&#46; aureus</span>&#44; MSSA&#44; and MRSA were compared in both cohorts&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Forty-&#64257;ve patients had <span class="elsevierStyleItalic">S&#46; aureus</span> HAP&#47;VAP in the EUVAP cohort vs&#46; 11 patients in the LATINVAP cohort&#46; More patients had MRSA in the LATINVAP study than in the EUVAP &#40;45&#37; vs&#46; 33&#37;&#41;&#46; ICU mortality among patients with MSSA HAP&#47;VAP in EUVAP was 10&#37; vs&#46; 50&#37; for LATINVAP &#40;OR &#61; 9&#46;75&#44; <span class="elsevierStyleItalic">p</span> &#61; 0&#46;01&#41;&#46; Fifteen patients in the EUVAP cohort developed MRSA HAP&#47;VAP as opposed to 5 in LATINVAP&#46; In the EUVAP study there was an ICU mortality rate of 33&#46;3&#37;&#46; In the LATINVAP cohort&#44; the ICU mortality rate was 60&#37; &#40;OR for death &#61; 3&#46;0&#59; 95&#37;CI 0&#46;24---44&#46;7&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">MRSA pneumonia was associated with poorer outcomes in comparison with MSSA&#46; Our study suggests signi&#64257;cant variability among European and Latin American ICU practices that may in&#64258;uence clinical outcomes&#46; Furthermore&#44; patients with pneumonia in Latin America have different outcomes&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">comparar las variables epidemiol&#243;gicas &#40;caracter&#237;sticas demogr&#225;&#64257;cas y cl&#237;nicas&#41; y los efectos en pacientes con neumon&#237;a intrahospitalaria &#40;NIH&#41; o neumon&#237;a asociada a la ventilaci&#243;n &#40;NAV&#41; causada por <span class="elsevierStyleItalic">Staphylococcus aureus</span> susceptible a la meticilina &#40;SASM&#41; y resistente a la meticilina &#40;SARM&#41; en las cohortes LATINVAP y EUVAP de pacientes admitidos en unidades de cuidados intensivos &#40;UCI&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El proyecto EUVAP fue un estudio prospectivo&#44; multic&#233;ntrico y observacional sobre 827 pacientes con NIH&#47;NAV de 27 UCI de 9 pa&#237;ses europeos&#46; El proyecto LATINVAP fue un estudio pospectivo&#44; multic&#233;ntrico y observacional de id&#233;ntico disen¿o que se llev&#243; a cabo en 17 UCI de 4 pa&#237;ses latinoamericanos y en el que se evaluaron 99 pacientes que hab&#237;an desarrollado HAP&#47;VAP&#46; Se compararon entre las cohortes los episodios de VAP&#47;HAP causados por <span class="elsevierStyleItalic">S&#46; aureus</span> &#40;SASM y SARM&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cuarenta y cinco pacientes presentaron NIH&#47;NAV por <span class="elsevierStyleItalic">S&#46; aureus</span> en la cohorte EUVAP frente a 11 pacientes en la cohorte LATINVAP&#46; El n&#250;mero de pacientes con SARM en el estudio LATINVAP fue superior al del estudio EUVAP &#40;45&#37; frente al 33&#37;&#41;&#46; La mortalidad en la UCI entre los pacientes con NIH&#47;NAV por SASM del estudio EUVAP fue del 10&#37; frente al 50&#37; en el caso del estudio LATINVAP &#40;OR &#61; 9&#44;75&#44; p &#61; 0&#44;01&#41;&#46; Quince pacientes de la cohorte EUVAP desarrollaron NIH&#47;NAV por SARM frente a 5 de la cohorte LATINVAP&#46; En el estudio EUVAP se registr&#243; una tasa de mortalidad del 33&#44;3&#37;&#46; En la cohorte LATINVAP la tasa de mortalidad en la UCI fue del 60&#37; &#40;OR de muerte &#61; 3&#44;0&#59; IC del 95&#37; de 0&#44;24 a 44&#44;7&#41;&#46;</p> <span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La neumon&#237;a por SARM se asoci&#243; a unos peores resultados en comparaci&#243;n con la neumon&#237;a por SASM&#46; Nuestro estudio sugiere una variabilidad importante entre las pr&#225;cticas de las UCI europeas y latinoamericanas que podr&#237;a in&#64258;uir sobre los resulta- dos cl&#237;nicos&#46; Adem&#225;s&#44; los pacientes con neumon&#237;a de Latinoam&#233;rica presentaron resultados diferentes&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Rello J&#46;&#44; et al&#46; Diferencias entre la neumon&#237;a de origen nosocomial y asociada a la ventilaci&#243;n por <span class="elsevierStyleItalic">Staphylococcus aureus</span> &#40;susceptible a la meticilina y resistente a la meticilina&#41; en europa y latinoam&#233;rica&#58; comparaci&#243;n de las cohortes de estudio EUVAP y LATINVAP&#46; Med Intensiva&#46; 2012&#46; http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;j&#46;medine&#46;2012&#46;04&#46;008&#46;</p>"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735727/0000003700000004/v1_201307160921/S2173572713000532/v1_201307160921/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "411"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735727/0000003700000004/v1_201307160921/S2173572713000532/v1_201307160921/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572713000532?idApp=WMIE"
]
Article information
ISSN: 21735727
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 4 13 17
2024 October 42 77 119
2024 September 33 47 80
2024 August 40 80 120
2024 July 45 61 106
2024 June 33 52 85
2024 May 32 40 72
2024 April 37 46 83
2024 March 39 52 91
2024 February 24 37 61
2024 January 28 36 64
2023 December 67 40 107
2023 November 30 44 74
2023 October 22 38 60
2023 September 32 47 79
2023 August 24 40 64
2023 July 34 34 68
2023 June 24 24 48
2023 May 35 33 68
2023 April 22 21 43
2023 March 30 39 69
2023 February 26 40 66
2023 January 19 43 62
2022 December 35 56 91
2022 November 28 51 79
2022 October 25 57 82
2022 September 36 51 87
2022 August 24 50 74
2022 July 23 56 79
2022 June 18 47 65
2022 May 21 52 73
2022 April 22 63 85
2022 March 26 75 101
2022 February 23 58 81
2022 January 29 38 67
2021 December 16 59 75
2021 November 25 63 88
2021 October 40 76 116
2021 September 24 61 85
2021 August 22 44 66
2021 July 20 41 61
2021 June 15 39 54
2021 May 29 53 82
2021 April 38 89 127
2021 March 30 42 72
2021 February 38 25 63
2021 January 28 39 67
2020 December 31 35 66
2020 November 13 24 37
2020 October 36 36 72
2020 September 34 28 62
2020 August 25 13 38
2020 July 15 13 28
2020 June 19 23 42
2020 May 19 19 38
2020 April 21 28 49
2020 March 15 20 35
2020 February 22 54 76
2020 January 21 37 58
2019 December 31 40 71
2019 November 22 27 49
2019 October 31 34 65
2019 September 29 31 60
2019 August 41 26 67
2019 July 27 34 61
2019 June 15 30 45
2019 May 43 62 105
2019 April 16 29 45
2019 March 12 26 38
2019 February 20 43 63
2019 January 20 28 48
2018 December 31 33 64
2018 November 46 77 123
2018 October 73 26 99
2018 September 27 15 42
2018 August 15 9 24
2018 July 30 9 39
2018 June 34 17 51
2018 May 11 5 16
2018 April 48 13 61
2018 March 19 14 33
2018 February 17 7 24
2018 January 21 14 35
2017 December 16 5 21
2017 November 20 8 28
2017 October 21 9 30
2017 September 16 7 23
2017 August 13 10 23
2017 July 14 6 20
2017 June 23 11 34
2017 May 14 8 22
2017 April 27 17 44
2017 March 18 14 32
2017 February 9 6 15
2017 January 9 5 14
2016 December 15 4 19
2016 November 14 8 22
2016 October 16 14 30
2016 September 32 10 42
2016 August 18 5 23
2016 July 15 3 18
2016 June 2 0 2
2016 April 1 0 1
2016 February 2 0 2
2015 December 2 0 2
2014 November 1 0 1
Show all

Follow this link to access the full text of the article

Idiomas
Medicina Intensiva (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?