array:23 [
  "pii" => "S2173572716300170"
  "issn" => "21735727"
  "doi" => "10.1016/j.medine.2015.08.006"
  "estado" => "S300"
  "fechaPublicacion" => "2016-06-01"
  "aid" => "834"
  "copyrightAnyo" => "2016"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Med Intensiva. 2016;40:289-97"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3215
    "formatos" => array:3 [
      "EPUB" => 164
      "HTML" => 2172
      "PDF" => 879
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0210569115001953"
      "issn" => "02105691"
      "doi" => "10.1016/j.medin.2015.08.002"
      "estado" => "S300"
      "fechaPublicacion" => "2016-06-01"
      "aid" => "834"
      "copyright" => "Elsevier España, S.L.U. y SEMICYUC"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Med Intensiva. 2016;40:289-97"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 5219
        "formatos" => array:3 [
          "EPUB" => 197
          "HTML" => 3774
          "PDF" => 1248
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Mortalidad y estado funcional al a&#241;o de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "289"
            "paginaFinal" => "297"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Mortality and functional status at one-year of follow-up in elderly patients with prolonged ICU stay"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 2115
                "Ancho" => 2781
                "Tamanyo" => 272309
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Diagrama de flujo&#46;</p> <p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">En la figura se muestra el diagrama de flujo de los pacientes incluidos en el estudio&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46;C&#46; Pintado, P&#46; Villa, J&#46; Luj&#225;n, M&#46; Trascasa, R&#46; Molina, N&#46; Gonz&#225;lez-Garc&#237;a, R&#46; de Pablo"
            "autores" => array:7 [
              0 => array:2 [
                "nombre" => "M&#46;C&#46;"
                "apellidos" => "Pintado"
              ]
              1 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "Villa"
              ]
              2 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Luj&#225;n"
              ]
              3 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Trascasa"
              ]
              4 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Molina"
              ]
              5 => array:2 [
                "nombre" => "N&#46;"
                "apellidos" => "Gonz&#225;lez-Garc&#237;a"
              ]
              6 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "de Pablo"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173572716300170"
          "doi" => "10.1016/j.medine.2015.08.006"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300170?idApp=WMIE"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569115001953?idApp=WMIE"
      "url" => "/02105691/0000004000000005/v1_201606170053/S0210569115001953/v1_201606170053/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2173572716300212"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2016.02.003"
    "estado" => "S300"
    "fechaPublicacion" => "2016-06-01"
    "aid" => "905"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "ssu"
    "cita" => "Med Intensiva. 2016;40:298-310"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 16480
      "formatos" => array:3 [
        "EPUB" => 280
        "HTML" => 12093
        "PDF" => 4107
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review</span>"
      "titulo" => "Massive obstetric hemorrhage&#58; Current approach to management"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "298"
          "paginaFinal" => "310"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Hemorragia masiva obst&#233;trica&#58; enfoque terap&#233;utico actual"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1141
              "Ancho" => 2170
              "Tamanyo" => 120410
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Protocol of Hospital Universitario La Paz for blood bank sample requests&#46; All patients undergo blood sampling upon admission to hospital&#44; with blood group typing and irregular antibody screening&#46; &#40;1&#41; In presumed low-risk deliveries&#58; no further studies are made&#46; &#40;2&#41; In the case of hemorrhage<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>500<span class="elsevierStyleHsp" style=""></span>ml&#44; elective or emergency cesarean section&#44; or presumed high-risk delivery &#40;twins&#44; anterior cesarean section&#44; placentation anomalies&#44; etc&#46;&#41;&#44; a second sample is sent to the blood bank for group confirmation&#44; thereby facilitating the availability of compatible blood if needed&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Guasch, F&#46; Gilsanz"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Guasch"
            ]
            1 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Gilsanz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S021056911630002X"
        "doi" => "10.1016/j.medin.2016.02.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021056911630002X?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300212?idApp=WMIE"
    "url" => "/21735727/0000004000000005/v1_201606250031/S2173572716300212/v1_201606250031/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S2173572716300194"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2015.09.003"
    "estado" => "S300"
    "fechaPublicacion" => "2016-06-01"
    "aid" => "853"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Med Intensiva. 2016;40:280-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2105
      "formatos" => array:3 [
        "EPUB" => 202
        "HTML" => 1222
        "PDF" => 681
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
      "titulo" => "Routine invasive strategy in acute coronary syndrome patients with renal dysfunction&#46; Results of the ARIAM-SEMICYUC registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "280"
          "paginaFinal" => "288"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Estrategia invasiva de rutina en el s&#237;ndrome coronario agudo sin elevaci&#243;n del segmento ST con disfunci&#243;n renal&#46; Resultados del registro ARIAM-SEMICYUC"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1194
              "Ancho" => 2266
              "Tamanyo" => 126294
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">In-hospital mortality and routine invasive strategy &#40;RIS&#41; utilization according to baseline risk&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; Latour-P&#233;rez, V&#46; G&#243;mez-Tello, E&#46; de-Miguel-Balsa, A&#46; Llamas-&#193;lvarez, A&#46; Carrillo-L&#243;pez, J&#46;A&#46; S&#225;nchez-Rom&#225;n, J&#46; Ru&#237;z-Ru&#237;z, M&#46;C&#46; Mart&#237;n-Rodr&#237;guez, C&#46;J&#46; Fern&#225;ndez-Gonz&#225;lez, J&#46;A&#46; Fern&#225;ndez-Lozano, C&#46; Picazos Vicente"
          "autores" => array:12 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Latour-P&#233;rez"
            ]
            1 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "G&#243;mez-Tello"
            ]
            2 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "de-Miguel-Balsa"
            ]
            3 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Llamas-&#193;lvarez"
            ]
            4 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Carrillo-L&#243;pez"
            ]
            5 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "S&#225;nchez-Rom&#225;n"
            ]
            6 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Ru&#237;z-Ru&#237;z"
            ]
            7 => array:2 [
              "nombre" => "M&#46;C&#46;"
              "apellidos" => "Mart&#237;n-Rodr&#237;guez"
            ]
            8 => array:2 [
              "nombre" => "C&#46;J&#46;"
              "apellidos" => "Fern&#225;ndez-Gonz&#225;lez"
            ]
            9 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "Fern&#225;ndez-Lozano"
            ]
            10 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Picazos Vicente"
            ]
            11 => array:1 [
              "colaborador" => "Grupo ARIAM-SEMICYUC"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0210569115002168"
        "doi" => "10.1016/j.medin.2015.09.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569115002168?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300194?idApp=WMIE"
    "url" => "/21735727/0000004000000005/v1_201606250031/S2173572716300194/v1_201606250031/en/main.assets"
  ]
  "en" => array:21 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
    "titulo" => "Mortality and functional status at one-year of follow-up in elderly patients with prolonged ICU stay"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "289"
        "paginaFinal" => "297"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46;C&#46; Pintado, P&#46; Villa, J&#46; Luj&#225;n, M&#46; Trascasa, R&#46; Molina, N&#46; Gonz&#225;lez-Garc&#237;a, R&#46; de Pablo"
        "autores" => array:7 [
          0 => array:4 [
            "nombre" => "M&#46;C&#46;"
            "apellidos" => "Pintado"
            "email" => array:1 [
              0 => "consuelopintado&#64;yahoo&#46;es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "Villa"
          ]
          2 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Luj&#225;n"
          ]
          3 => array:2 [
            "nombre" => "M&#46;"
            "apellidos" => "Trascasa"
          ]
          4 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Molina"
          ]
          5 => array:2 [
            "nombre" => "N&#46;"
            "apellidos" => "Gonz&#225;lez-Garc&#237;a"
          ]
          6 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "de Pablo"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Unidad de Cuidados Intensivos&#44; Hospital Universitario Pr&#237;ncipe de Asturias&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Mortalidad y estado funcional al a&#241;o de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2076
            "Ancho" => 2372
            "Tamanyo" => 219523
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">Functional status in the course of the study&#46; The figures show the evolution of functional status as scored with the Barthel index in the course of the study in the two groups&#58; prolonged admission and short stay&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">There is growing interest in the sequelae of admission to the Intensive Care Unit &#40;ICU&#41;&#44; though the data published to date in this regard are quite heterogeneous&#46; Some authors<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">1&#8211;5</span></a> have found such patients to have poorer quality of life and greater mortality than the gender- and age-matched general population until several years after admission to Intensive Care&#46; In contrast&#44; other investigators<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#8211;12</span></a> have observed acceptable recovery in the months following discharge from the ICU&#46; A number of factors have been associated to increased morbidity-mortality after discharge from the ICU&#44; including patient age&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;4&#44;13&#44;14</span></a> the duration of admission to the ICU&#44;<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#44;13</span></a> the severity of the disease condition&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;13&#44;14</span></a> previous comorbidities&#44; the basal situation of the patient&#44;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">4</span></a> and the diagnosis motivating admission to the UCI&#46;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;13</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Considering the growing number of elderly patients admitted to our Units&#44;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">15</span></a> a dilemma has developed regarding the long-term benefits of admission to the ICU in this population group&#46; The literature offers conflicting results in this respect&#46; Some studies have found that although mortality both in the ICU and after discharge from the Unit is high among elderly patients and greater than in younger individuals&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;7&#44;13&#44;15&#8211;17</span></a> functional status and quality of life one year after discharge among the survivors are very similar to how they were before admission to the ICU&#8211;thereby justifying admission to these Units&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">7&#44;9&#44;17</span></a> In contrast&#44; other studies have described a clear worsening of quality of life among the survivors&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">16&#44;18</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The dilemma intensifies when considering elderly people who are admitted to the ICU for long periods of time&#46; What are the mortality figures among these patients after discharge from the ICU&#63; What is their functional status after discharge from the ICU&#63; What quality of life do the survivors have&#63; etc&#46; Although there is no clear consensus as to what we mean by &#8220;prolonged admission&#8221; to the ICU&#8211;the definitions typically ranging from 2 to 4 weeks<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">5&#44;6&#44;9&#44;11&#8211;13&#44;19&#44;20</span></a>&#8211;the literature shows that although mortality one year after discharge is high among survivors of prolonged admission to the ICU&#44; their quality of life is good&#44; with high rates of functional independence&#46;<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#44;8&#44;12&#44;13&#44;16&#44;17&#44;21</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The present study analyzes mortality and functional status after one year among elderly patients &#40;over 75 years of age&#41; with prolonged admission to the ICU &#40;over 14 days&#41;&#44; and establishes comparisons with elderly patients who have been admitted to the ICU for shorter periods of time&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Patients and methods</span><p id="par0025" class="elsevierStylePara elsevierViewall">A prospective observational study was made in a 14-bed polyvalent ICU belonging to a tertiary hospital&#44; covering a period of 18 months &#40;from 1 December 2009 to 31 May 2011&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We included all patients over 75 years of age admitted to the ICU for more than 14 days and who agreed to participate in the study &#40;through signing of the informed consent document by the patient&#47;closest relatives&#41;&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">At patient inclusion in the study we recorded the demographic variables &#40;age and gender&#41;&#44; comorbidities &#40;as assessed by the Charlson comorbidity index<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">22</span></a>&#41;&#44; basal functional status &#40;as measured by the Barthel index &#91;BI&#93;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a>&#41;&#44; basal mental state &#40;measured using the Red Cross Psychic Disability scale &#91;RCPD&#93;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">24</span></a>&#41;&#44; place of residency&#44; reason for admission to the ICU&#44; and severity of the disease &#40;evaluated by means of the Acute Physiology and Chronic Health Evaluation II &#91;APACHE II&#93;<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">25</span></a> and the Sequential-Related Organ Failure Assessment &#91;SOFA&#93; scale<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a>&#41;&#46; At discharge from the ICU we collected information on stay and mortality in the Unit&#44; the need for mechanical ventilation and its duration&#44; the need for vasoactive drug support&#44; and the presence of multiorgan failure &#40;defined as a score of 3 or 4 on the SOFA scale<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a> referred to two or more organs&#41;&#46; At hospital discharge we assessed mental and functional status&#44; patient destination at discharge&#44; and in-hospital stay and mortality&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The patients were followed-up on during one year after discharge from the ICU by means of a telephone interview at 3&#44; 6 and 12 months&#44; documenting mental and functional status &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> and RCPD scale<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">24</span></a>&#41;&#44; mortality&#44; place of residency and the number of hospital readmissions&#46; On occasion of the interview after 12 months&#44; the patients were asked whether they would be prepared to enter the ICU again if necessary&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Basal functional status was defined as the functional status of the patient in the month before admission&#44; and the stay in the ICU was considered to be prolonged if it exceeded 14 days&#44; and short if &#8804;14 days&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Functional status was divided into 5 levels according to the BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a>&#58; total dependency &#40;&#60;20 points&#41;&#44; severe dependency &#40;20&#8211;35 points&#41;&#44; moderate dependency &#40;40&#8211;55 points&#41;&#44; slight dependency &#40;60&#8211;95 points&#41;&#44; and independence &#40;100 points&#41;&#46; Dependent patients were regarded as those with total&#44; severe or moderate dependency functional status &#40;BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> &#60;60&#41;&#46; Significant worsening of functional status in turn was defined by a decrease in BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> of 20 points or more&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The study was approved by the Clinical Research Ethics Committee of the hospital&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Statistical analysis</span><p id="par0060" class="elsevierStylePara elsevierViewall">The statistical analysis of the results was carried out using the SPSS version 18&#46;0 statistical package &#40;SPSS Inc&#46;&#44; Chicago&#44; IL&#44; USA&#41;&#46; Qualitative variables were reported as numbers and percentages&#44; and were analyzed using the chi-squared test in the case of unpaired variables&#44; and the McNemar test or McNemar&#8211;Bowker test in the case of paired binary variables of two or more categories&#44; respectively&#46; In the case of quantitative variables we first assessed normality of the distribution using the Kolmogorov&#8211;Smirnov test&#46; Those variables exhibiting a normal distribution were reported as the mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#44; and were analyzed using the Student <span class="elsevierStyleItalic">t</span>-test for unpaired variables or the Student&#8211;Fisher test in the case of paired data&#46; Quantitative variables with a non-normal distribution were reported as the median and interquartile range&#44; and were analyzed using the Wilcoxon test or marginal homogeneity test &#40;according to the number of categories&#41; in the case of paired variables&#44; and the nonparametric Mann&#8211;Whitney <span class="elsevierStyleItalic">U</span>-test in the case of unpaired variables&#46;</p></span></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Results</span><p id="par0065" class="elsevierStylePara elsevierViewall">During the study period&#44; a total of 177 patients over 75 years of age were admitted to our ICU&#59; of these subjects&#44; one rejected participation in the study&#46; Twenty-two of the 176 patients finally included in the study were admitted to the ICU for over 14 days &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Although there were no differences in terms of gender&#44; comorbidities or basal mental and physical status&#44; the patients requiring prolonged admission were younger and presented greater severity upon admission as measured by both the APACHE II<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">25</span></a> and the SOFA<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a> scale&#46; The main cause of admission to the ICU among the patients with prolonged admission was infectious disease &#40;59&#46;1&#37;&#41;&#44; while cardiovascular disease was seen to predominate among the short stay patients &#40;59&#46;7&#37;&#41;&#46; <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the basal characteristics of the patients over 75 years of age upon admission to the ICU&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">All the patients requiring prolonged admission to the ICU also required mechanical ventilation and vasoactive drug support&#44; and 18&#46;2&#37; moreover required renal replacement therapy &#8211; all of them presenting multiorgan failure &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46; This situation in turn explained the increased severity among these patients&#44; as reflected by a poorer daily SOFA score &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">Forty-eight patients died during admission to the ICU &#40;global mortality rate in the ICU&#58; 27&#46;3&#37;&#41;&#46; Although the patients with prolonged admission suffered comparatively greater mortality&#44; we observed no statistically significant differences between the two groups &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">After discharge from the ICU&#44; 18 patients died during their stay in hospital&#8211;the in-hospital mortality rate being higher among the patients with prolonged admission &#40;63&#46;6&#37; vs 33&#46;8&#37;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; Functional deterioration was observed in the patients at hospital discharge&#44; as evidenced by a drop in the BI score&#44;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> which proved more notorious in the case of the patients with prolonged admission &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> 100&#46;00 &#91;90&#46;00&#8211;100&#46;00&#93; upon admission vs 10&#46;00 &#91;5&#46;00&#8211;55&#46;00&#93; at hospital discharge&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; The BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> at discharge in these patients was lower than in the patients with short stays &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> at hospital discharge 85&#46;00 &#91;50&#46;00&#8211;100&#46;00&#93; in patients with short stays vs 10&#46;00 &#91;5&#46;00&#8211;55&#46;00&#93; in patients with prolonged stays&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#44; despite the absence of differences in this regard at the time of admission to the ICU&#46; This decrease in BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> was significant &#40;&#8805;20 points&#41; in all the patients with prolonged admission &#40;100&#37; vs 32&#46;7&#37;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; A total of 4&#46;5&#37; of the patients in the prolonged admission group had been dependent before admission to the ICU&#44; versus 10&#46;9&#37; of the patients with short admission &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;70&#41;&#46; In turn&#44; the dependency rate at hospital discharge was 85&#46;7&#37; in the prolonged admission group versus 28&#46;8&#37; in the short stay group &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In contrast&#44; no significant differences were observed between the two groups in terms of mental status at discharge versus mental status upon admission&#46; In this regard&#44; 77&#46;3&#37; of the patients with prolonged stays presented a normal mental status upon admission to the ICU&#44; and this situation was seen to persist in 80&#37; of them at discharge &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;35&#41;&#46; In the case of the patients with short stays&#44; 71&#46;9&#37; presented no mental alterations upon admission&#44; and this situation persisted in 92&#46;3&#37; of them at discharge &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;08&#41;&#46;</p><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Follow-up after one year</span><p id="par0090" class="elsevierStylePara elsevierViewall">A total of 79&#46;8&#37; of the patients with a short stay in the ICU were still alive at hospital discharge&#8211;a figure that dropped to only 53&#46;8&#37; among those with prolonged admission to the ICU &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;07&#41;&#46; This difference in mortality was largely attributable to in-hospital deaths&#44; since follow-up one year after hospital discharge showed 90&#46;4&#37; of the survivors to be still alive &#40;87&#46;5&#37; of those in the prolonged admission group and 90&#46;6&#37; in the short stay group&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;57&#41;&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">We observed no differences in the percentage of hospital readmissions during the year of follow-up between the two patient groups &#40;100&#37; in the patients with prolonged stays vs 74&#46;5&#37; in the patients with short stays&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;00&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">On comparing the evolution of functional status among the patients according to the duration of admission to the ICU&#44; we found the subjects with prolonged admission to have a poorer functional status both at hospital discharge &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> 10&#46;00 &#91;5&#46;00&#8211;55&#46;00&#93; vs 85&#46;00 &#91;50&#46;00&#8211;100&#46;00&#93;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41; and after three months of follow-up &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> 65&#46;00 &#91;5&#46;00&#8211;96&#46;25&#93; vs 95&#46;00 &#91;80&#46;00&#8211;100&#46;00&#93;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;04&#41; than the patients with short stays&#46; Although an improvement in functional status was noted at 6 and 12 months in both groups&#44; the differences between the patients with prolonged admission and those with short stays were not significant &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Despite the improvements at follow-up&#44; 50&#37; of the patients with prolonged admission to the ICU and 16&#46;9&#37; of those with short stays suffered significant loss of function &#40;as reflected by a drop in BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> of &#8805;20 points&#41; after one year with respect to the time of admission&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0105" class="elsevierStylePara elsevierViewall">At one year of follow-up&#44; functional status was found to be poorer than under basal conditions in both groups&#8211;though the loss of independence was more manifest &#40;without reaching statistical significance&#41; in the prolonged admission group&#44; with an independency rate after one year of 66&#46;7&#37; versus 95&#46;5&#37; at the time of admission&#44; while the short stay group showed an independency rate after one year of 85&#46;1&#37; versus 89&#46;1&#37; at the time of admission &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">With regard to patient mental status after one year&#44; the subjects with prolonged stay in the ICU showed no differences at either discharge or after one year with respect to their mental status upon admission&#8211;most of the subjects maintaining normal mental function or with slight alterations referred to orientation in time&#44; independently of the duration of stay in the ICU &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0115" class="elsevierStylePara elsevierViewall">Seventy-five percent of the patients who survived prolonged admission to the ICU lived at home prior to admission&#44; though only 37&#46;5&#37; returned home after hospital discharge&#46; This percentage increased to 50&#37; after one year of follow-up&#46; In contrast&#44; 68&#46;4&#37; of the patients who survived a short stay in the ICU returned home after discharge&#8211;a figure that increased to 75&#46;7&#37; after one year&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Only 49 patients answered the question as to whether they would be prepared to enter the ICU again if necessary because of the disease&#8211;no differences being observed according to the duration of admission to intensive care&#58; 100&#37; of the patients with prolonged admission to the ICU versus 76&#46;1&#37; of those with short stays stated that they would accept admission to the ICU again if necessary &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;00&#41;&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Discussion</span><p id="par0125" class="elsevierStylePara elsevierViewall">In our study we found the proportion of elderly patients with prolonged admission to the ICU to be low&#44; though the mortality rates both in the ICU and in hospital were high and greater than among the patients with a short stay in the ICU&#46; Furthermore&#44; the patients in the prolonged admission group suffered important deterioration of functional status after hospital discharge&#44; without recovery of their basal situation after one year of follow-up&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">The mortality rate in the ICU in our series was 27&#46;3&#37;&#44; which is consistent with the rates reported in the literature for elderly patients &#40;23&#8211;62&#46;5&#37;&#41;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">9&#44;16&#44;19&#44;27&#8211;29</span></a>&#8211;the published figures varying greatly according to the cutoff point considered &#40;65&#8211;80 years&#41;&#46; We recorded a tendency towards increased mortality in patients with prolonged admission&#44; in coincidence with the findings of other studies both in adults<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#44;12</span></a> and specifically in elderly subjects&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">19</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">Although the patients with prolonged admission presented greater severity upon admission to intensive care&#44; and therefore also a poorer prognosis&#44; they were found to be relatively younger&#46; This age difference may have influenced the limitation of therapeutic effort&#44; independently of the severity of the disease&#44; with a possibly earlier decision to limit such effort in the older patients&#46; Likewise&#44; in-hospital mortality among the patients with prolonged admission to the ICU was found to be high and greater than in those with shorter stays&#46; A review of the literature yielded no similar studies allowing comparisons to be made with our own mortality figures&#46; We only identified two studies in patients over 70 years of age and with stays of over 30 days&#46; The respective mortality rates were 33&#37; and 23&#37;&#44; with no statistically significant differences versus patients with shorter stays&#46;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">9&#44;19</span></a></p><p id="par0140" class="elsevierStylePara elsevierViewall">Despite the high in-hospital mortality recorded in our study&#44; most of the patients who survived admission to hospital were still alive after one year&#46; Montuclard et al&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a> reported a similar estimated survival rate of 41<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#37; after one year in patients over 70 years of age and with stays of more than 30 days&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">On examining what happens with the survivors in relation to functional status&#44; the latter was seen to have clearly worsened at the time of hospital discharge&#44; and although the situation improved over the following months &#40;particularly in the first three months of follow-up&#41;&#44; functional status failed to return to the levels observed prior to admission to the ICU&#46; This deterioration was more notorious in the patients with prolonged admission&#46; Few studies have analyzed functional status over the long term in elderly patients who survive admission to the ICU&#44; and the results are moreover heterogeneous&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">16&#44;17&#44;30&#8211;33</span></a> Only one study has examined what happens in elderly subjects who survive prolonged &#40;&#62;30 days&#41; admission to the ICU&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a> The authors recorded a worsening of general functional status &#40;except as regards eating&#41; 557<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>117 days after discharge from the ICU&#44; though most of the patients remained independent for their activities of daily living&#46; This coincides with our own observations&#44; since 60&#37; of the patients with prolonged admission were found to be independent after one year of follow-up&#46; In our case&#44; the situation among the patients with prolonged admission to intensive care was worse than in those with short stays&#44; with lower independence rates&#44; and therefore with fewer subjects able to return home during the first year after discharge&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">We observed no significant differences in patient mental status after versus before hospital admission&#44; not even after one year of follow-up&#44; independently of the duration of admission to the ICU&#46; No studies have been made on the mental sequelae after one year in elderly patients with prolonged admission to the ICU&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">As regards the question of whether the patients with prolonged admissions would be willing to enter the ICU again if necessary&#44; we found that most of the survivors would accept readmission&#46; Similar results have been obtained by Montuclard et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a> since 83&#46;3&#37; of their elderly patients who were still alive one year after prolonged admission to the ICU would accept returning to the ICU if necessary&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">As regards the limitations of our study&#44; mention must be made of its single-centre nature&#44; with a limited number of patients who were moreover selected on the grounds of a good basal status &#40;both mental and physical&#41;&#44; and with low comorbidity as previously described<a class="elsevierStyleCrossRef" href="#bib0350"><span class="elsevierStyleSup">34</span></a> and also seen in similar studies&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">16&#44;28&#44;35&#44;36</span></a> Furthermore&#44; we did not record the limitation of therapeutic effort rates&#44; which could have been interesting for better analysis of the data&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">In conclusion&#44; we found that patients over 75 years of age with prolonged admission to the ICU suffer high mortality both in the ICU and in hospital&#44; and such mortality is moreover greater than in patients requiring shorter stays in intensive care&#46; Nevertheless&#44; the survivors of prolonged admission to the ICU show a high survival rate after one year&#8211;though functional status is poorer than before admission to the ICU&#44; despite slight improvement during the year of follow-up&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conflict of interest</span><p id="par0170" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres678045"
          "titulo" => "Abstract"
          "secciones" => array:7 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Objective"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Design"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Setting"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Patients"
            ]
            4 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Primary variables of interest"
            ]
            5 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Results"
            ]
            6 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec684017"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres678046"
          "titulo" => "Resumen"
          "secciones" => array:7 [
            0 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Objetivo"
            ]
            1 => array:2 [
              "identificador" => "abst0045"
              "titulo" => "Dise&#241;o"
            ]
            2 => array:2 [
              "identificador" => "abst0050"
              "titulo" => "&#193;mbito"
            ]
            3 => array:2 [
              "identificador" => "abst0055"
              "titulo" => "Pacientes"
            ]
            4 => array:2 [
              "identificador" => "abst0060"
              "titulo" => "Variables de inter&#233;s principales"
            ]
            5 => array:2 [
              "identificador" => "abst0065"
              "titulo" => "Resultados"
            ]
            6 => array:2 [
              "identificador" => "abst0070"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec684016"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Patients and methods"
          "secciones" => array:1 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Statistical analysis"
            ]
          ]
        ]
        6 => array:3 [
          "identificador" => "sec0020"
          "titulo" => "Results"
          "secciones" => array:1 [
            0 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Follow-up after one year"
            ]
          ]
        ]
        7 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflict of interest"
        ]
        9 => array:2 [
          "identificador" => "xack228635"
          "titulo" => "Acknowledgements"
        ]
        10 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2015-03-20"
    "fechaAceptado" => "2015-08-07"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec684017"
          "palabras" => array:5 [
            0 => "Elderly"
            1 => "Prognosis"
            2 => "Long-term outcome"
            3 => "Health-related quality of life"
            4 => "Critical care"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec684016"
          "palabras" => array:5 [
            0 => "Ancianos"
            1 => "Pron&#243;stico"
            2 => "Resultado a largo plazo"
            3 => "Calidad de vida relacionada con la salud"
            4 => "Cuidados intensivos"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate mortality and functional status at one year of follow-up in patients &#62;75 years of age who survive Intensive Care Unit &#40;ICU&#41; admission of over 14 days&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Design</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A prospective observational study was carried out&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Setting</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A Spanish medical&#8211;surgical ICU&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Patients</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Patients over 75 years of age admitted to the ICU&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Primary variables of interest</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">ICU admission&#58; demographic data&#44; baseline functional status &#40;Barthel index&#41;&#44; baseline mental status &#40;Red Cross scale of mental incapacity&#41;&#44; severity of illness &#40;APACHE II and SOFA&#41;&#44; stay and mortality&#46; One-year follow-up&#58; hospital stay and mortality&#44; functional and mental status&#44; and one-year follow-up mortality&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Results</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A total of 176 patients were included&#44; of which 22 had a stay of over 14 days&#46; Patients with prolonged stay did not show more ICU mortality than those with a shorter stay in the ICU &#40;40&#46;9&#37; vs 25&#46;3&#37; respectively&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;12&#41;&#44; although their hospital &#40;63&#46;6&#37; vs 33&#46;8&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;01&#41; and one-year follow-up mortality were higher &#40;68&#46;2&#37; vs 41&#46;2&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41;&#46; Among the survivors&#44; one-year mortality proved similar &#40;87&#46;5&#37; vs 90&#46;6&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;57&#41;&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">These patients presented significantly greater impairment of functional status at hospital discharge than the patients with a shorter ICU stay&#44; and this difference persisted after three months&#46; The levels of independence at one-year follow-up were never similar to baseline&#46; No such findings were observed in relation to mental status&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Patients over 75 years of age with a ICU stay of more than 14 days have high hospital and one-year follow-up mortality&#46; Patients who survive to hospital admission did not show greater mortality&#44; though their functional dependency was greater&#46;</p></span>"
        "secciones" => array:7 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objective"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Design"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Setting"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Patients"
          ]
          4 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Primary variables of interest"
          ]
          5 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Results"
          ]
          6 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Objetivo</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Determinar la mortalidad y situaci&#243;n funcional al a&#241;o de los pacientes mayores de 75 a&#241;os con estancia en una unidad de cuidados intensivos &#40;UCI&#41; mayor de 14 d&#237;as&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Dise&#241;o</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Estudio prospectivo observacional&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">&#193;mbito</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">UCI m&#233;dico-quir&#250;rgica espa&#241;ola&#46;</p></span> <span id="abst0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Pacientes</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Pacientes mayores de 75 a&#241;os ingresados en UCI&#46;</p></span> <span id="abst0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Variables de inter&#233;s principales</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Ingreso en UCI&#58; datos demogr&#225;ficos&#44; estado funcional basal &#40;&#237;ndice de Barthel&#41;&#44; estado mental basal &#40;Escala de incapacidad mental de la Cruz Roja&#41;&#44; gravedad de la enfermedad &#40;APACHE II y SOFA&#41;&#44; mortalidad y estancia&#46; Seguimiento al a&#241;o&#58; estancia&#47;mortalidad hospitalaria&#44; situaci&#243;n funcional y mental y mortalidad al a&#241;o&#46;</p></span> <span id="abst0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Incluimos 176 pacientes&#44; 22 con una estancia mayor de 14 d&#237;as&#46; Los pacientes con estancias prolongadas no presentaron mayor mortalidad en UCI que los de menor estancia &#40;40&#44;9&#37; vs&#46; 25&#44;3&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;12&#41;&#44; aunque su mortalidad hospitalaria &#40;63&#44;6&#37; vs&#46; 33&#44;8&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41; y al a&#241;o &#40;68&#44;2&#37; vs&#46; 41&#44;2&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41; fue superior&#46; Entre los supervivientes la supervivencia al a&#241;o fue similar &#40;87&#44;5&#37; vs&#46; 90&#44;6&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;57&#41;&#46;</p><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Estos pacientes presentaron un deterioro en su situaci&#243;n funcional al alta hospitalaria significativamente mayor que los de corta estancia&#44; diferencia que se mantuvo a los 3 meses&#46; Nunca llegaron a alcanzar niveles de independencia previos al ingreso durante el a&#241;o&#46; Estos hallazgos no se observaron a nivel mental&#46;</p></span> <span id="abst0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Conclusiones</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Los pacientes mayores de 75 a&#241;os con estancia en UCI mayor de 14 d&#237;as presentan una mortalidad hospitalaria y al a&#241;o elevada&#46; Los pacientes que logran ser dados de alta del hospital no presentan mayor mortalidad&#44; aunque s&#237; presentan mayor grado de dependencia funcional&#46;</p></span>"
        "secciones" => array:7 [
          0 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0045"
            "titulo" => "Dise&#241;o"
          ]
          2 => array:2 [
            "identificador" => "abst0050"
            "titulo" => "&#193;mbito"
          ]
          3 => array:2 [
            "identificador" => "abst0055"
            "titulo" => "Pacientes"
          ]
          4 => array:2 [
            "identificador" => "abst0060"
            "titulo" => "Variables de inter&#233;s principales"
          ]
          5 => array:2 [
            "identificador" => "abst0065"
            "titulo" => "Resultados"
          ]
          6 => array:2 [
            "identificador" => "abst0070"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0020">Please cite this article as&#58; Pintado MC&#44; Villa P&#44; Luj&#225;n J&#44; Trascasa M&#44; Molina R&#44; Gonz&#225;lez-Garc&#237;a N&#44; et al&#46; Mortalidad y estado funcional al a&#241;o de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos&#46; Med Intensiva&#46; 2016&#59;40&#58;289&#8211;297&#46;</p>"
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2115
            "Ancho" => 2781
            "Tamanyo" => 243892
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Flowchart&#46; The figure shows the flowchart of the patients included in the study&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2076
            "Ancho" => 2372
            "Tamanyo" => 219523
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">Functional status in the course of the study&#46; The figures show the evolution of functional status as scored with the Barthel index in the course of the study in the two groups&#58; prolonged admission and short stay&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2825
            "Ancho" => 2045
            "Tamanyo" => 300989
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">Mental status&#46; The figures show the evolution of mental status as scored with the Red Cross Psychic Disability scale in the course of the study in the two groups&#58; prolonged admission and short stay&#46; No significant differences were found on comparing the different moments of the study &#40;basal&#44; hospital discharge and follow-up during one year&#41; in each group or between groups&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0105" class="elsevierStyleSimplePara elsevierViewall">The results are presented as number and percentage&#44; except&#58;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Short stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>154&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Prolonged stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>-Value&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Age</span><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#46;82<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">79&#46;27<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#46;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Age group</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62;75&#8211;80 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70 &#40;45&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;68&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>81&#8211;85 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54 &#40;35&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;27&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62;85 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">30 &#40;19&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Gender&#58; male&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">75 &#40;48&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;59&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Charlson score<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;67<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;32<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Comorbidity</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Low&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">79 &#40;51&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;54&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Moderate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41 &#40;26&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;36&#46;40&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>High&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34 &#40;22&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Barthel index<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;00 &#40;80&#46;00&#8211;100&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&#46;00 &#40;90&#46;00&#8211;100&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;42&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Degree of functional dependency</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;76&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Independent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68 &#40;49&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;54&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Slight dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54 &#40;39&#46;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;40&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Moderate dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;7&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Severe dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;2&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Total dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Functional dependency &#40;BI &#60; 60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;10&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;70&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Red Cross psychic disability scale</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Completely normal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97 &#40;71&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;77&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Slight disorientation in time&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;18&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;13&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Disorientation in time&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;9&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Reason for admission</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cardiovascular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">92 &#40;59&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;13&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Infectious&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;18&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;59&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Respiratory&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;3&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;13&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Resuscitated cardiac arrest&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;6&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Neurological&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;3&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Intoxications&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Digestive&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Surgery&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;3&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Techniques&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>APACHE II<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#46;50 &#40;11&#46;00&#8211;24&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#46;00 &#40;19&#46;00&#8211;28&#46;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>SOFA<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;00 &#40;1&#46;00&#8211;8&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;00 &#40;7&#46;00&#8211;12&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1112755.png"
              ]
            ]
          ]
          "notaPie" => array:2 [
            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Median &#40;percentile<span class="elsevierStyleInf">25</span>&#8211;percentile<span class="elsevierStyleInf">75</span>&#41;&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">Basal characteristics of the patients over 75 years of age admitted to the ICU according to the duration of stay&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">The results are presented as number and percentage&#44; except&#58;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Short stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>154&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Prolonged stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>-Value&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Presence of multiorgan failure&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">56 &#40;36&#46;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;100&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Mechanical ventilation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">57 &#40;37&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;100&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Vasoactive drug support&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">86 &#40;55&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;100&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Renal replacement therapy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;18&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Poorer SOFA score<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;00 &#40;2&#46;00&#8211;10&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;00 &#40;8&#46;75&#8211;12&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Stay in ICU &#40;days&#41;<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;00 &#40;2&#46;00&#8211;5&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">32&#46;00 &#40;17&#46;00&#8211;45&#46;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Hospital stay &#40;days&#41;<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;00 &#40;6&#46;00&#8211;16&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#46;00 &#40;27&#46;00&#8211;71&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Mortality in ICU&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">39 &#40;25&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;40&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Mortality in hospital&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52 &#40;33&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;63&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1112756.png"
              ]
            ]
          ]
          "notaPie" => array:1 [
            0 => array:3 [
              "identificador" => "tblfn0015"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Median &#40;percentile<span class="elsevierStyleInf">25</span>&#8211;percentile<span class="elsevierStyleInf">75</span>&#41;&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0110" class="elsevierStyleSimplePara elsevierViewall">Evolution of the patients during admission to the ICU according to the duration of stay&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:36 [
            0 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The impact of critical illness on perceived health-related quality of life during ICU treatment&#44; hospital stay&#44; and after hospital discharge&#58; a long-term follow-up study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;G&#46; Hofhuis"
                            1 => "P&#46;E&#46; Spronk"
                            2 => "H&#46;F&#46; van Stel"
                            3 => "G&#46;J&#46; Schrijvers"
                            4 => "J&#46;H&#46; Rommes"
                            5 => "J&#46; Bakker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.07-1217"
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2008"
                        "volumen" => "133"
                        "paginaInicial" => "377"
                        "paginaFinal" => "385"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17925419"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673612602402"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Persistent organ dysfunction plus death&#58; a novel&#44; composite outcome measure for critical care trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;K&#46; Heyland"
                            1 => "J&#46; Muscedere"
                            2 => "J&#46; Drover"
                            3 => "X&#46; Jiang"
                            4 => "A&#46;G&#46; Day"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc10110"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "R98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21418560"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Determinants of long-term survival after intensive care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46;A&#46; Williams"
                            1 => "G&#46;J&#46; Dobb"
                            2 => "J&#46;C&#46; Finn"
                            3 => "M&#46;W&#46; Knuiman"
                            4 => "E&#46; Geelhoed"
                            5 => "K&#46;Y&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e318170a405"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "1523"
                        "paginaFinal" => "1530"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18434893"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Post-Intensive Care Unit mortality and related prognostic factors in a cohort of critically ill patients with multi-organ dysfunction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "V&#46;A&#46; Hortiguela-Martin"
                            1 => "M&#46; Sanchez-Casado"
                            2 => "S&#46; Rodriguez-Villar"
                            3 => "M&#46; Quintana-D&#237;az"
                            4 => "C&#46; Marco-Shulke"
                            5 => "V&#46; G&#243;mez-Tello"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2013"
                        "volumen" => "140"
                        "paginaInicial" => "479"
                        "paginaFinal" => "486"
                        "itemHostRev" => array:3 [
                          "pii" => "S095461111300173X"
                          "estado" => "S300"
                          "issn" => "09546111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mortality after hospital discharge in ICU patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Brinkman"
                            1 => "E&#46; de Jonge"
                            2 => "A&#46; Abu-Hanna"
                            3 => "M&#46;S&#46; Arbous"
                            4 => "D&#46;W&#46; de Lange"
                            5 => "N&#46;F&#46; de Keizer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e31827ca4e1"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2013"
                        "volumen" => "41"
                        "paginaInicial" => "1229"
                        "paginaFinal" => "1236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23591209"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term mortality outcome associated with prolonged admission to the ICU"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;B&#46; Laupland"
                            1 => "A&#46;W&#46; Kirkpatrick"
                            2 => "J&#46;B&#46; Kortbeek"
                            3 => "D&#46;J&#46; Zuege"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.129.4.954"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2006"
                        "volumen" => "129"
                        "paginaInicial" => "954"
                        "paginaFinal" => "959"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16608944"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes of health-related quality of life in critically ill octogenarians&#58; a follow-up study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;G&#46; Hofhuis"
                            1 => "H&#46;F&#46; van Stel"
                            2 => "A&#46;J&#46; Schrijvers"
                            3 => "J&#46;H&#46; Rommes"
                            4 => "P&#46;E&#46; Spronk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.10-0803"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2011"
                        "volumen" => "140"
                        "paginaInicial" => "1473"
                        "paginaFinal" => "1483"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21960698"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome and mortality risk factors in long-term treated ICU patients&#58; a retrospective analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Bickenbach"
                            1 => "M&#46; Fries"
                            2 => "S&#46; Rex"
                            3 => "C&#46; Stitz"
                            4 => "N&#46; Heussen"
                            5 => "R&#46; Rossaint"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Minerva Anestesiol"
                        "fecha" => "2011"
                        "volumen" => "77"
                        "paginaInicial" => "427"
                        "paginaFinal" => "438"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21483387"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome&#44; functional autonomy&#44; and quality of life of elderly patients with a long-term intensive care unit stay"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "L&#46; Montuclard"
                            1 => "Garrouste-Org"
                            2 => "J&#46;F&#46; Timsit"
                            3 => "B&#46; Misset"
                            4 => "B&#46; de Jonghe"
                            5 => "J&#46; Carlet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "28"
                        "paginaInicial" => "3389"
                        "paginaFinal" => "3395"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11057791"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome and functional capacity after prolonged intensive care unit stay"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;G&#46; Delle"
                            1 => "B&#46; Meyer"
                            2 => "S&#46; Bauer"
                            3 => "M&#46; Nikfardjam"
                            4 => "G&#46; Heinz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00508-006-0616-z"
                      "Revista" => array:6 [
                        "tituloSerie" => "Wien Klin Wochenschr"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "390"
                        "paginaFinal" => "396"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16865643"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival and quality of life after a long-term intensive care stay"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46; Isgro"
                            1 => "J&#46;A&#46; Skuras"
                            2 => "A&#46;H&#46; Kiessling"
                            3 => "A&#46; Lehmann"
                            4 => "W&#46; Saggau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1055/s-2002-26693"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorac Cardiovasc Surg"
                        "fecha" => "2002"
                        "volumen" => "50"
                        "paginaInicial" => "95"
                        "paginaFinal" => "99"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11981710"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Morbidity&#44; mortality&#44; and quality-of-life outcomes of patients requiring &#8805;14 days of mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Combes"
                            1 => "M&#46;A&#46; Costa"
                            2 => "J&#46;L&#46; Trouillet"
                            3 => "J&#46; Baudot"
                            4 => "M&#46; Mokhtari"
                            5 => "C&#46; Gibert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000065188.87029.C3"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2003"
                        "volumen" => "31"
                        "paginaInicial" => "1373"
                        "paginaFinal" => "1381"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12771605"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term outcome of long stay ICU and HDU patients in a New Zealand Hospital"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;P&#46; Carden"
                            1 => "J&#46;W&#46; Graham"
                            2 => "S&#46; McLennan"
                            3 => "L&#46;A&#46; Celi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Shock"
                        "fecha" => "2008"
                        "volumen" => "11"
                        "paginaInicial" => "26"
                        "paginaFinal" => "34"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23766668"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short- and long-term survival of nonsurgical intensive care patients and its relation to diagnosis&#44; severity of disease&#44; age and comorbidities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;A&#46; Kaufmann"
                            1 => "K&#46;H&#46; Smolle"
                            2 => "G&#46;J&#46; Krejs"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Aging Sci"
                        "fecha" => "2009"
                        "volumen" => "2"
                        "paginaInicial" => "240"
                        "paginaFinal" => "248"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20021418"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The eldicus prospective&#44; observational study of triage decision making in European intensive care units&#46; Part II&#58; intensive care benefit for the elderly"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;L&#46; Sprung"
                            1 => "A&#46; Artigas"
                            2 => "J&#46; Kesecioglu"
                            3 => "A&#46; Pezzi"
                            4 => "J&#46; Wiis"
                            5 => "R&#46; Pirracchio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e318232d6b0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2012"
                        "volumen" => "40"
                        "paginaInicial" => "132"
                        "paginaFinal" => "138"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22001580"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Decision-making process&#44; outcome&#44; and 1-year quality of life of octogenarians referred for intensive care unit admission"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Garrouste-Org"
                            1 => "J&#46;F&#46; Timsit"
                            2 => "L&#46; Montuclard"
                            3 => "A&#46; Colvez"
                            4 => "O&#46; Gattolliat"
                            5 => "F&#46; Philippart"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00134-006-0169-7"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "2006"
                        "volumen" => "32"
                        "paginaInicial" => "1045"
                        "paginaFinal" => "1051"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16791667"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Functional status and quality of life 12 months after discharge from a medical ICU in healthy elderly patients&#58; a prospective observational study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Sacanella"
                            1 => "J&#46;M&#46; Perez-Castejon"
                            2 => "J&#46;M&#46; Nicolas"
                            3 => "F&#46; Masanes"
                            4 => "M&#46; Navarro"
                            5 => "P&#46; Castro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc10121"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "R105"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21443796"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Five-year survival and prognostic factors in a cohort of hospitalized nonagenarians"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Conde-Martel"
                            1 => "M&#46; Hemmersbach-Miller"
                            2 => "J&#46; Marchena-Gomez"
                            3 => "P&#46; Saavedra-Santana"
                            4 => "P&#46; Betancor-Leon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ejim.2012.02.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Intern Med"
                        "fecha" => "2012"
                        "volumen" => "23"
                        "paginaInicial" => "513"
                        "paginaFinal" => "518"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22863427"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and prognosis of patients with very long stay in an Intensive Care Unit"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46;L&#46; Santana"
                            1 => "M&#46; Sanchez-Palacios"
                            2 => "M&#46;E&#46; Hernandez"
                            3 => "R&#46;P&#46; Eugenio"
                            4 => "A&#46; Villanueva-Hernandez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Intensiva"
                        "fecha" => "2008"
                        "volumen" => "32"
                        "paginaInicial" => "157"
                        "paginaFinal" => "162"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18413119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is it &#8216;worthwhile&#8217; to continue treating patients with a prolonged stay &#40;&#62;14 days&#41; in the ICU&#63; An economic evaluation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;K&#46; Heyland"
                            1 => "E&#46; Konopad"
                            2 => "T&#46;W&#46; Noseworthy"
                            3 => "R&#46; Johnston"
                            4 => "A&#46; Gafni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1998"
                        "volumen" => "114"
                        "paginaInicial" => "192"
                        "paginaFinal" => "198"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9674469"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Disability in activities of daily living&#44; depression&#44; and quality of life among older medical ICU survivors&#58; a prospective cohort study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;T&#46; Vest"
                            1 => "T&#46;E&#46; Murphy"
                            2 => "K&#46;L&#46; Araujo"
                            3 => "M&#46;A&#46; Pisani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1477-7525-9-9"
                      "Revista" => array:5 [
                        "tituloSerie" => "Health Qual Life Outcomes"
                        "fecha" => "2011"
                        "volumen" => "9"
                        "paginaInicial" => "9"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21294911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A new method of classifying prognostic comorbidity in longitudinal studies&#58; development and validation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;E&#46; Charlson"
                            1 => "P&#46; Pompei"
                            2 => "K&#46;L&#46; Ales"
                            3 => "C&#46;R&#46; MacKenzie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Chronic Dis"
                        "fecha" => "1987"
                        "volumen" => "40"
                        "paginaInicial" => "373"
                        "paginaFinal" => "383"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3558716"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Functional evaluation&#58; the Barthel Index"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46;I&#46; Mahoney"
                            1 => "D&#46;W&#46; Barthel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Md State Med J"
                        "fecha" => "1965"
                        "volumen" => "14"
                        "paginaInicial" => "61"
                        "paginaFinal" => "65"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5832033"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ayuda a domicilio&#46; Aspectos m&#233;dicos en geriatr&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Guill&#233;n Llera"
                            1 => "A&#46; Garc&#237;a Ant&#243;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Esp Gerontol"
                        "fecha" => "1972"
                        "volumen" => "7"
                        "paginaInicial" => "339"
                        "paginaFinal" => "346"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0305"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "APACHE II&#58; a severity of disease classification system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46;A&#46; Knaus"
                            1 => "E&#46;A&#46; Draper"
                            2 => "D&#46;P&#46; Wagner"
                            3 => "J&#46;E&#46; Zimmerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "1985"
                        "volumen" => "13"
                        "paginaInicial" => "818"
                        "paginaFinal" => "829"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3928249"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0310"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of the SOFA score to assess the incidence of organ dysfunction&#47;failure in intensive care units&#58; results of a multicenter&#44; prospective study&#46; Working group on &#171;sepsis-related problems&#187; of the European Society of Intensive Care Medicine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;L&#46; Vincent"
                            1 => "A&#46; de Mendonca"
                            2 => "F&#46; Cantraine"
                            3 => "R&#46; Moreno"
                            4 => "J&#46; Takala"
                            5 => "P&#46;M&#46; Suter"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "1998"
                        "volumen" => "26"
                        "paginaInicial" => "1793"
                        "paginaFinal" => "1800"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9824069"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0315"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term survival&#44; quality of life&#44; and quality-adjusted life-years among critically ill elderly patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Kaarlola"
                            1 => "M&#46; Tallgren"
                            2 => "V&#46; Pettila"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000227656.31911.2E"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2006"
                        "volumen" => "34"
                        "paginaInicial" => "2120"
                        "paginaFinal" => "2126"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16763517"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0320"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Variability of intensive care admission decisions for the very elderly"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Boumendil"
                            1 => "D&#46;C&#46; Angus"
                            2 => "A&#46;L&#46; Guitonneau"
                            3 => "A&#46;M&#46; Menn"
                            4 => "C&#46; Ginsburg"
                            5 => "K&#46; Takun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0034387"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2012"
                        "volumen" => "7"
                        "paginaInicial" => "e34387"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22509296"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0325"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acceptable long-term outcome in elderly intensive care unit patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;A&#46; Schroder"
                            1 => "J&#46;B&#46; Poulsen"
                            2 => "A&#46; Perner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dan Med Bull"
                        "fecha" => "2011"
                        "volumen" => "58"
                        "paginaInicial" => "A4297"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21722543"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0330"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in patients aged 80 or over after ICU discharge"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Tabah"
                            1 => "F&#46; Philippart"
                            2 => "J&#46;F&#46; Timsit"
                            3 => "V&#46; Willems"
                            4 => "A&#46; Francais"
                            5 => "A&#46; Leplege"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc8231"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2010"
                        "volumen" => "14"
                        "paginaInicial" => "R2"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20064197"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0335"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cognitive&#44; functional&#44; and quality-of-life outcomes of patients aged 80 and older who survived at least 1 year after planned or unplanned surgery or medical intensive care treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46;E&#46; De Rooij"
                            1 => "A&#46;C&#46; Govers"
                            2 => "J&#46;C&#46; Korevaar"
                            3 => "A&#46;W&#46; Giesbers"
                            4 => "M&#46; Levi"
                            5 => "E&#46; de Jonge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1532-5415.2008.01671.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Geriatr Soc"
                        "fecha" => "2008"
                        "volumen" => "56"
                        "paginaInicial" => "816"
                        "paginaFinal" => "822"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18384589"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0340"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Geriatric conditions in acutely hospitalized older patients&#58; prevalence and one-year survival and functional decline"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;M&#46; Buurman"
                            1 => "J&#46;G&#46; Hoogerduijn"
                            2 => "R&#46;J&#46; de Haan"
                            3 => "A&#46; Abu-Hanna"
                            4 => "A&#46;M&#46; Lagaay"
                            5 => "H&#46;J&#46; Verhaar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0026951"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2011"
                        "volumen" => "6"
                        "paginaInicial" => "e26951"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22110598"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0345"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term outcome of critically ill elderly patients requiring intensive care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46; Chelluri"
                            1 => "M&#46;R&#46; Pinsky"
                            2 => "M&#46;P&#46; Donahoe"
                            3 => "A&#46; Grenvik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "1993"
                        "volumen" => "269"
                        "paginaInicial" => "3119"
                        "paginaFinal" => "3123"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8505814"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0350"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and outcomes of elderly patients refused to ICU"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;C&#46; Pintado"
                            1 => "P&#46; Villa"
                            2 => "N&#46; Gonzalez-Garcia"
                            3 => "J&#46; Lujan"
                            4 => "R&#46; Molina"
                            5 => "M&#46; Trascasa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Sci World J"
                        "fecha" => "2013"
                        "volumen" => "2013"
                        "paginaInicial" => "590837"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0355"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reasons for refusal of admission to intensive care and impact on mortality"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Iapichino"
                            1 => "D&#46; Corbella"
                            2 => "C&#46; Minelli"
                            3 => "G&#46;H&#46; Mills"
                            4 => "A&#46; Artigas"
                            5 => "D&#46;L&#46; Edbooke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00134-010-1933-2"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "2010"
                        "volumen" => "36"
                        "paginaInicial" => "1772"
                        "paginaFinal" => "1779"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20533023"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0360"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of triage decisions for intensive care admission"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;L&#46; Sprung"
                            1 => "D&#46; Geber"
                            2 => "L&#46;A&#46; Eidelman"
                            3 => "M&#46; Baras"
                            4 => "R&#46; Pizov"
                            5 => "A&#46; Nimrod"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "27"
                        "paginaInicial" => "1073"
                        "paginaFinal" => "1079"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10397207"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
    "agradecimientos" => array:1 [
      0 => array:4 [
        "identificador" => "xack228635"
        "titulo" => "Acknowledgements"
        "texto" => "<p id="par0175" class="elsevierStylePara elsevierViewall">Thanks are due to all the patients and personnel members who made this study possible&#46;</p>"
        "vista" => "all"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735727/0000004000000005/v1_201606250031/S2173572716300170/v1_201606250031/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/21735727/0000004000000005/v1_201606250031/S2173572716300170/v1_201606250031/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300170?idApp=WMIE"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Original
Mortality and functional status at one-year of follow-up in elderly patients with prolonged ICU stay
Mortalidad y estado funcional al año de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos
M.C. Pintado
Corresponding author
consuelopintado@yahoo.es

Corresponding author.
, P. Villa, J. Luján, M. Trascasa, R. Molina, N. González-García, R. de Pablo
Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
Read
9346
Times
was read the article
3168
Total PDF
6178
Total HTML
Share statistics
 array:23 [
  "pii" => "S2173572716300170"
  "issn" => "21735727"
  "doi" => "10.1016/j.medine.2015.08.006"
  "estado" => "S300"
  "fechaPublicacion" => "2016-06-01"
  "aid" => "834"
  "copyrightAnyo" => "2016"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Med Intensiva. 2016;40:289-97"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3215
    "formatos" => array:3 [
      "EPUB" => 164
      "HTML" => 2172
      "PDF" => 879
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0210569115001953"
      "issn" => "02105691"
      "doi" => "10.1016/j.medin.2015.08.002"
      "estado" => "S300"
      "fechaPublicacion" => "2016-06-01"
      "aid" => "834"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; y SEMICYUC"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Med Intensiva. 2016;40:289-97"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 5219
        "formatos" => array:3 [
          "EPUB" => 197
          "HTML" => 3774
          "PDF" => 1248
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Mortalidad y estado funcional al a&#241;o de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "289"
            "paginaFinal" => "297"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Mortality and functional status at one-year of follow-up in elderly patients with prolonged ICU stay"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 2115
                "Ancho" => 2781
                "Tamanyo" => 272309
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Diagrama de flujo&#46;</p> <p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">En la figura se muestra el diagrama de flujo de los pacientes incluidos en el estudio&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46;C&#46; Pintado, P&#46; Villa, J&#46; Luj&#225;n, M&#46; Trascasa, R&#46; Molina, N&#46; Gonz&#225;lez-Garc&#237;a, R&#46; de Pablo"
            "autores" => array:7 [
              0 => array:2 [
                "nombre" => "M&#46;C&#46;"
                "apellidos" => "Pintado"
              ]
              1 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "Villa"
              ]
              2 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Luj&#225;n"
              ]
              3 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Trascasa"
              ]
              4 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Molina"
              ]
              5 => array:2 [
                "nombre" => "N&#46;"
                "apellidos" => "Gonz&#225;lez-Garc&#237;a"
              ]
              6 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "de Pablo"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173572716300170"
          "doi" => "10.1016/j.medine.2015.08.006"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300170?idApp=WMIE"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569115001953?idApp=WMIE"
      "url" => "/02105691/0000004000000005/v1_201606170053/S0210569115001953/v1_201606170053/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2173572716300212"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2016.02.003"
    "estado" => "S300"
    "fechaPublicacion" => "2016-06-01"
    "aid" => "905"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "ssu"
    "cita" => "Med Intensiva. 2016;40:298-310"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 16480
      "formatos" => array:3 [
        "EPUB" => 280
        "HTML" => 12093
        "PDF" => 4107
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review</span>"
      "titulo" => "Massive obstetric hemorrhage&#58; Current approach to management"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "298"
          "paginaFinal" => "310"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Hemorragia masiva obst&#233;trica&#58; enfoque terap&#233;utico actual"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1141
              "Ancho" => 2170
              "Tamanyo" => 120410
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Protocol of Hospital Universitario La Paz for blood bank sample requests&#46; All patients undergo blood sampling upon admission to hospital&#44; with blood group typing and irregular antibody screening&#46; &#40;1&#41; In presumed low-risk deliveries&#58; no further studies are made&#46; &#40;2&#41; In the case of hemorrhage<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>500<span class="elsevierStyleHsp" style=""></span>ml&#44; elective or emergency cesarean section&#44; or presumed high-risk delivery &#40;twins&#44; anterior cesarean section&#44; placentation anomalies&#44; etc&#46;&#41;&#44; a second sample is sent to the blood bank for group confirmation&#44; thereby facilitating the availability of compatible blood if needed&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Guasch, F&#46; Gilsanz"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Guasch"
            ]
            1 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Gilsanz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S021056911630002X"
        "doi" => "10.1016/j.medin.2016.02.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021056911630002X?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300212?idApp=WMIE"
    "url" => "/21735727/0000004000000005/v1_201606250031/S2173572716300212/v1_201606250031/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S2173572716300194"
    "issn" => "21735727"
    "doi" => "10.1016/j.medine.2015.09.003"
    "estado" => "S300"
    "fechaPublicacion" => "2016-06-01"
    "aid" => "853"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Med Intensiva. 2016;40:280-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2105
      "formatos" => array:3 [
        "EPUB" => 202
        "HTML" => 1222
        "PDF" => 681
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
      "titulo" => "Routine invasive strategy in acute coronary syndrome patients with renal dysfunction&#46; Results of the ARIAM-SEMICYUC registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "280"
          "paginaFinal" => "288"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Estrategia invasiva de rutina en el s&#237;ndrome coronario agudo sin elevaci&#243;n del segmento ST con disfunci&#243;n renal&#46; Resultados del registro ARIAM-SEMICYUC"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1194
              "Ancho" => 2266
              "Tamanyo" => 126294
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">In-hospital mortality and routine invasive strategy &#40;RIS&#41; utilization according to baseline risk&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; Latour-P&#233;rez, V&#46; G&#243;mez-Tello, E&#46; de-Miguel-Balsa, A&#46; Llamas-&#193;lvarez, A&#46; Carrillo-L&#243;pez, J&#46;A&#46; S&#225;nchez-Rom&#225;n, J&#46; Ru&#237;z-Ru&#237;z, M&#46;C&#46; Mart&#237;n-Rodr&#237;guez, C&#46;J&#46; Fern&#225;ndez-Gonz&#225;lez, J&#46;A&#46; Fern&#225;ndez-Lozano, C&#46; Picazos Vicente"
          "autores" => array:12 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Latour-P&#233;rez"
            ]
            1 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "G&#243;mez-Tello"
            ]
            2 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "de-Miguel-Balsa"
            ]
            3 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Llamas-&#193;lvarez"
            ]
            4 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Carrillo-L&#243;pez"
            ]
            5 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "S&#225;nchez-Rom&#225;n"
            ]
            6 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Ru&#237;z-Ru&#237;z"
            ]
            7 => array:2 [
              "nombre" => "M&#46;C&#46;"
              "apellidos" => "Mart&#237;n-Rodr&#237;guez"
            ]
            8 => array:2 [
              "nombre" => "C&#46;J&#46;"
              "apellidos" => "Fern&#225;ndez-Gonz&#225;lez"
            ]
            9 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "Fern&#225;ndez-Lozano"
            ]
            10 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Picazos Vicente"
            ]
            11 => array:1 [
              "colaborador" => "Grupo ARIAM-SEMICYUC"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0210569115002168"
        "doi" => "10.1016/j.medin.2015.09.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569115002168?idApp=WMIE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300194?idApp=WMIE"
    "url" => "/21735727/0000004000000005/v1_201606250031/S2173572716300194/v1_201606250031/en/main.assets"
  ]
  "en" => array:21 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
    "titulo" => "Mortality and functional status at one-year of follow-up in elderly patients with prolonged ICU stay"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "289"
        "paginaFinal" => "297"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46;C&#46; Pintado, P&#46; Villa, J&#46; Luj&#225;n, M&#46; Trascasa, R&#46; Molina, N&#46; Gonz&#225;lez-Garc&#237;a, R&#46; de Pablo"
        "autores" => array:7 [
          0 => array:4 [
            "nombre" => "M&#46;C&#46;"
            "apellidos" => "Pintado"
            "email" => array:1 [
              0 => "consuelopintado&#64;yahoo&#46;es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "Villa"
          ]
          2 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Luj&#225;n"
          ]
          3 => array:2 [
            "nombre" => "M&#46;"
            "apellidos" => "Trascasa"
          ]
          4 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Molina"
          ]
          5 => array:2 [
            "nombre" => "N&#46;"
            "apellidos" => "Gonz&#225;lez-Garc&#237;a"
          ]
          6 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "de Pablo"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Unidad de Cuidados Intensivos&#44; Hospital Universitario Pr&#237;ncipe de Asturias&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Mortalidad y estado funcional al a&#241;o de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2076
            "Ancho" => 2372
            "Tamanyo" => 219523
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">Functional status in the course of the study&#46; The figures show the evolution of functional status as scored with the Barthel index in the course of the study in the two groups&#58; prolonged admission and short stay&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">There is growing interest in the sequelae of admission to the Intensive Care Unit &#40;ICU&#41;&#44; though the data published to date in this regard are quite heterogeneous&#46; Some authors<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">1&#8211;5</span></a> have found such patients to have poorer quality of life and greater mortality than the gender- and age-matched general population until several years after admission to Intensive Care&#46; In contrast&#44; other investigators<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#8211;12</span></a> have observed acceptable recovery in the months following discharge from the ICU&#46; A number of factors have been associated to increased morbidity-mortality after discharge from the ICU&#44; including patient age&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;4&#44;13&#44;14</span></a> the duration of admission to the ICU&#44;<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#44;13</span></a> the severity of the disease condition&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;13&#44;14</span></a> previous comorbidities&#44; the basal situation of the patient&#44;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">4</span></a> and the diagnosis motivating admission to the UCI&#46;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;13</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Considering the growing number of elderly patients admitted to our Units&#44;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">15</span></a> a dilemma has developed regarding the long-term benefits of admission to the ICU in this population group&#46; The literature offers conflicting results in this respect&#46; Some studies have found that although mortality both in the ICU and after discharge from the Unit is high among elderly patients and greater than in younger individuals&#44;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">3&#44;7&#44;13&#44;15&#8211;17</span></a> functional status and quality of life one year after discharge among the survivors are very similar to how they were before admission to the ICU&#8211;thereby justifying admission to these Units&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">7&#44;9&#44;17</span></a> In contrast&#44; other studies have described a clear worsening of quality of life among the survivors&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">16&#44;18</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The dilemma intensifies when considering elderly people who are admitted to the ICU for long periods of time&#46; What are the mortality figures among these patients after discharge from the ICU&#63; What is their functional status after discharge from the ICU&#63; What quality of life do the survivors have&#63; etc&#46; Although there is no clear consensus as to what we mean by &#8220;prolonged admission&#8221; to the ICU&#8211;the definitions typically ranging from 2 to 4 weeks<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">5&#44;6&#44;9&#44;11&#8211;13&#44;19&#44;20</span></a>&#8211;the literature shows that although mortality one year after discharge is high among survivors of prolonged admission to the ICU&#44; their quality of life is good&#44; with high rates of functional independence&#46;<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#44;8&#44;12&#44;13&#44;16&#44;17&#44;21</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The present study analyzes mortality and functional status after one year among elderly patients &#40;over 75 years of age&#41; with prolonged admission to the ICU &#40;over 14 days&#41;&#44; and establishes comparisons with elderly patients who have been admitted to the ICU for shorter periods of time&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Patients and methods</span><p id="par0025" class="elsevierStylePara elsevierViewall">A prospective observational study was made in a 14-bed polyvalent ICU belonging to a tertiary hospital&#44; covering a period of 18 months &#40;from 1 December 2009 to 31 May 2011&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We included all patients over 75 years of age admitted to the ICU for more than 14 days and who agreed to participate in the study &#40;through signing of the informed consent document by the patient&#47;closest relatives&#41;&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">At patient inclusion in the study we recorded the demographic variables &#40;age and gender&#41;&#44; comorbidities &#40;as assessed by the Charlson comorbidity index<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">22</span></a>&#41;&#44; basal functional status &#40;as measured by the Barthel index &#91;BI&#93;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a>&#41;&#44; basal mental state &#40;measured using the Red Cross Psychic Disability scale &#91;RCPD&#93;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">24</span></a>&#41;&#44; place of residency&#44; reason for admission to the ICU&#44; and severity of the disease &#40;evaluated by means of the Acute Physiology and Chronic Health Evaluation II &#91;APACHE II&#93;<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">25</span></a> and the Sequential-Related Organ Failure Assessment &#91;SOFA&#93; scale<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a>&#41;&#46; At discharge from the ICU we collected information on stay and mortality in the Unit&#44; the need for mechanical ventilation and its duration&#44; the need for vasoactive drug support&#44; and the presence of multiorgan failure &#40;defined as a score of 3 or 4 on the SOFA scale<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a> referred to two or more organs&#41;&#46; At hospital discharge we assessed mental and functional status&#44; patient destination at discharge&#44; and in-hospital stay and mortality&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The patients were followed-up on during one year after discharge from the ICU by means of a telephone interview at 3&#44; 6 and 12 months&#44; documenting mental and functional status &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> and RCPD scale<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">24</span></a>&#41;&#44; mortality&#44; place of residency and the number of hospital readmissions&#46; On occasion of the interview after 12 months&#44; the patients were asked whether they would be prepared to enter the ICU again if necessary&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Basal functional status was defined as the functional status of the patient in the month before admission&#44; and the stay in the ICU was considered to be prolonged if it exceeded 14 days&#44; and short if &#8804;14 days&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Functional status was divided into 5 levels according to the BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a>&#58; total dependency &#40;&#60;20 points&#41;&#44; severe dependency &#40;20&#8211;35 points&#41;&#44; moderate dependency &#40;40&#8211;55 points&#41;&#44; slight dependency &#40;60&#8211;95 points&#41;&#44; and independence &#40;100 points&#41;&#46; Dependent patients were regarded as those with total&#44; severe or moderate dependency functional status &#40;BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> &#60;60&#41;&#46; Significant worsening of functional status in turn was defined by a decrease in BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> of 20 points or more&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The study was approved by the Clinical Research Ethics Committee of the hospital&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Statistical analysis</span><p id="par0060" class="elsevierStylePara elsevierViewall">The statistical analysis of the results was carried out using the SPSS version 18&#46;0 statistical package &#40;SPSS Inc&#46;&#44; Chicago&#44; IL&#44; USA&#41;&#46; Qualitative variables were reported as numbers and percentages&#44; and were analyzed using the chi-squared test in the case of unpaired variables&#44; and the McNemar test or McNemar&#8211;Bowker test in the case of paired binary variables of two or more categories&#44; respectively&#46; In the case of quantitative variables we first assessed normality of the distribution using the Kolmogorov&#8211;Smirnov test&#46; Those variables exhibiting a normal distribution were reported as the mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#44; and were analyzed using the Student <span class="elsevierStyleItalic">t</span>-test for unpaired variables or the Student&#8211;Fisher test in the case of paired data&#46; Quantitative variables with a non-normal distribution were reported as the median and interquartile range&#44; and were analyzed using the Wilcoxon test or marginal homogeneity test &#40;according to the number of categories&#41; in the case of paired variables&#44; and the nonparametric Mann&#8211;Whitney <span class="elsevierStyleItalic">U</span>-test in the case of unpaired variables&#46;</p></span></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Results</span><p id="par0065" class="elsevierStylePara elsevierViewall">During the study period&#44; a total of 177 patients over 75 years of age were admitted to our ICU&#59; of these subjects&#44; one rejected participation in the study&#46; Twenty-two of the 176 patients finally included in the study were admitted to the ICU for over 14 days &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Although there were no differences in terms of gender&#44; comorbidities or basal mental and physical status&#44; the patients requiring prolonged admission were younger and presented greater severity upon admission as measured by both the APACHE II<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">25</span></a> and the SOFA<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a> scale&#46; The main cause of admission to the ICU among the patients with prolonged admission was infectious disease &#40;59&#46;1&#37;&#41;&#44; while cardiovascular disease was seen to predominate among the short stay patients &#40;59&#46;7&#37;&#41;&#46; <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the basal characteristics of the patients over 75 years of age upon admission to the ICU&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">All the patients requiring prolonged admission to the ICU also required mechanical ventilation and vasoactive drug support&#44; and 18&#46;2&#37; moreover required renal replacement therapy &#8211; all of them presenting multiorgan failure &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46; This situation in turn explained the increased severity among these patients&#44; as reflected by a poorer daily SOFA score &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">Forty-eight patients died during admission to the ICU &#40;global mortality rate in the ICU&#58; 27&#46;3&#37;&#41;&#46; Although the patients with prolonged admission suffered comparatively greater mortality&#44; we observed no statistically significant differences between the two groups &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">After discharge from the ICU&#44; 18 patients died during their stay in hospital&#8211;the in-hospital mortality rate being higher among the patients with prolonged admission &#40;63&#46;6&#37; vs 33&#46;8&#37;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; Functional deterioration was observed in the patients at hospital discharge&#44; as evidenced by a drop in the BI score&#44;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> which proved more notorious in the case of the patients with prolonged admission &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> 100&#46;00 &#91;90&#46;00&#8211;100&#46;00&#93; upon admission vs 10&#46;00 &#91;5&#46;00&#8211;55&#46;00&#93; at hospital discharge&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; The BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> at discharge in these patients was lower than in the patients with short stays &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> at hospital discharge 85&#46;00 &#91;50&#46;00&#8211;100&#46;00&#93; in patients with short stays vs 10&#46;00 &#91;5&#46;00&#8211;55&#46;00&#93; in patients with prolonged stays&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#44; despite the absence of differences in this regard at the time of admission to the ICU&#46; This decrease in BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> was significant &#40;&#8805;20 points&#41; in all the patients with prolonged admission &#40;100&#37; vs 32&#46;7&#37;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; A total of 4&#46;5&#37; of the patients in the prolonged admission group had been dependent before admission to the ICU&#44; versus 10&#46;9&#37; of the patients with short admission &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;70&#41;&#46; In turn&#44; the dependency rate at hospital discharge was 85&#46;7&#37; in the prolonged admission group versus 28&#46;8&#37; in the short stay group &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In contrast&#44; no significant differences were observed between the two groups in terms of mental status at discharge versus mental status upon admission&#46; In this regard&#44; 77&#46;3&#37; of the patients with prolonged stays presented a normal mental status upon admission to the ICU&#44; and this situation was seen to persist in 80&#37; of them at discharge &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;35&#41;&#46; In the case of the patients with short stays&#44; 71&#46;9&#37; presented no mental alterations upon admission&#44; and this situation persisted in 92&#46;3&#37; of them at discharge &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;08&#41;&#46;</p><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Follow-up after one year</span><p id="par0090" class="elsevierStylePara elsevierViewall">A total of 79&#46;8&#37; of the patients with a short stay in the ICU were still alive at hospital discharge&#8211;a figure that dropped to only 53&#46;8&#37; among those with prolonged admission to the ICU &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;07&#41;&#46; This difference in mortality was largely attributable to in-hospital deaths&#44; since follow-up one year after hospital discharge showed 90&#46;4&#37; of the survivors to be still alive &#40;87&#46;5&#37; of those in the prolonged admission group and 90&#46;6&#37; in the short stay group&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;57&#41;&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">We observed no differences in the percentage of hospital readmissions during the year of follow-up between the two patient groups &#40;100&#37; in the patients with prolonged stays vs 74&#46;5&#37; in the patients with short stays&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;00&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">On comparing the evolution of functional status among the patients according to the duration of admission to the ICU&#44; we found the subjects with prolonged admission to have a poorer functional status both at hospital discharge &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> 10&#46;00 &#91;5&#46;00&#8211;55&#46;00&#93; vs 85&#46;00 &#91;50&#46;00&#8211;100&#46;00&#93;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41; and after three months of follow-up &#40;BI<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> 65&#46;00 &#91;5&#46;00&#8211;96&#46;25&#93; vs 95&#46;00 &#91;80&#46;00&#8211;100&#46;00&#93;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;04&#41; than the patients with short stays&#46; Although an improvement in functional status was noted at 6 and 12 months in both groups&#44; the differences between the patients with prolonged admission and those with short stays were not significant &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Despite the improvements at follow-up&#44; 50&#37; of the patients with prolonged admission to the ICU and 16&#46;9&#37; of those with short stays suffered significant loss of function &#40;as reflected by a drop in BI score<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a> of &#8805;20 points&#41; after one year with respect to the time of admission&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0105" class="elsevierStylePara elsevierViewall">At one year of follow-up&#44; functional status was found to be poorer than under basal conditions in both groups&#8211;though the loss of independence was more manifest &#40;without reaching statistical significance&#41; in the prolonged admission group&#44; with an independency rate after one year of 66&#46;7&#37; versus 95&#46;5&#37; at the time of admission&#44; while the short stay group showed an independency rate after one year of 85&#46;1&#37; versus 89&#46;1&#37; at the time of admission &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">With regard to patient mental status after one year&#44; the subjects with prolonged stay in the ICU showed no differences at either discharge or after one year with respect to their mental status upon admission&#8211;most of the subjects maintaining normal mental function or with slight alterations referred to orientation in time&#44; independently of the duration of stay in the ICU &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0115" class="elsevierStylePara elsevierViewall">Seventy-five percent of the patients who survived prolonged admission to the ICU lived at home prior to admission&#44; though only 37&#46;5&#37; returned home after hospital discharge&#46; This percentage increased to 50&#37; after one year of follow-up&#46; In contrast&#44; 68&#46;4&#37; of the patients who survived a short stay in the ICU returned home after discharge&#8211;a figure that increased to 75&#46;7&#37; after one year&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Only 49 patients answered the question as to whether they would be prepared to enter the ICU again if necessary because of the disease&#8211;no differences being observed according to the duration of admission to intensive care&#58; 100&#37; of the patients with prolonged admission to the ICU versus 76&#46;1&#37; of those with short stays stated that they would accept admission to the ICU again if necessary &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;00&#41;&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Discussion</span><p id="par0125" class="elsevierStylePara elsevierViewall">In our study we found the proportion of elderly patients with prolonged admission to the ICU to be low&#44; though the mortality rates both in the ICU and in hospital were high and greater than among the patients with a short stay in the ICU&#46; Furthermore&#44; the patients in the prolonged admission group suffered important deterioration of functional status after hospital discharge&#44; without recovery of their basal situation after one year of follow-up&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">The mortality rate in the ICU in our series was 27&#46;3&#37;&#44; which is consistent with the rates reported in the literature for elderly patients &#40;23&#8211;62&#46;5&#37;&#41;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">9&#44;16&#44;19&#44;27&#8211;29</span></a>&#8211;the published figures varying greatly according to the cutoff point considered &#40;65&#8211;80 years&#41;&#46; We recorded a tendency towards increased mortality in patients with prolonged admission&#44; in coincidence with the findings of other studies both in adults<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">6&#44;12</span></a> and specifically in elderly subjects&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">19</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">Although the patients with prolonged admission presented greater severity upon admission to intensive care&#44; and therefore also a poorer prognosis&#44; they were found to be relatively younger&#46; This age difference may have influenced the limitation of therapeutic effort&#44; independently of the severity of the disease&#44; with a possibly earlier decision to limit such effort in the older patients&#46; Likewise&#44; in-hospital mortality among the patients with prolonged admission to the ICU was found to be high and greater than in those with shorter stays&#46; A review of the literature yielded no similar studies allowing comparisons to be made with our own mortality figures&#46; We only identified two studies in patients over 70 years of age and with stays of over 30 days&#46; The respective mortality rates were 33&#37; and 23&#37;&#44; with no statistically significant differences versus patients with shorter stays&#46;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">9&#44;19</span></a></p><p id="par0140" class="elsevierStylePara elsevierViewall">Despite the high in-hospital mortality recorded in our study&#44; most of the patients who survived admission to hospital were still alive after one year&#46; Montuclard et al&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a> reported a similar estimated survival rate of 41<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#37; after one year in patients over 70 years of age and with stays of more than 30 days&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">On examining what happens with the survivors in relation to functional status&#44; the latter was seen to have clearly worsened at the time of hospital discharge&#44; and although the situation improved over the following months &#40;particularly in the first three months of follow-up&#41;&#44; functional status failed to return to the levels observed prior to admission to the ICU&#46; This deterioration was more notorious in the patients with prolonged admission&#46; Few studies have analyzed functional status over the long term in elderly patients who survive admission to the ICU&#44; and the results are moreover heterogeneous&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">16&#44;17&#44;30&#8211;33</span></a> Only one study has examined what happens in elderly subjects who survive prolonged &#40;&#62;30 days&#41; admission to the ICU&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a> The authors recorded a worsening of general functional status &#40;except as regards eating&#41; 557<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>117 days after discharge from the ICU&#44; though most of the patients remained independent for their activities of daily living&#46; This coincides with our own observations&#44; since 60&#37; of the patients with prolonged admission were found to be independent after one year of follow-up&#46; In our case&#44; the situation among the patients with prolonged admission to intensive care was worse than in those with short stays&#44; with lower independence rates&#44; and therefore with fewer subjects able to return home during the first year after discharge&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">We observed no significant differences in patient mental status after versus before hospital admission&#44; not even after one year of follow-up&#44; independently of the duration of admission to the ICU&#46; No studies have been made on the mental sequelae after one year in elderly patients with prolonged admission to the ICU&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">As regards the question of whether the patients with prolonged admissions would be willing to enter the ICU again if necessary&#44; we found that most of the survivors would accept readmission&#46; Similar results have been obtained by Montuclard et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a> since 83&#46;3&#37; of their elderly patients who were still alive one year after prolonged admission to the ICU would accept returning to the ICU if necessary&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">As regards the limitations of our study&#44; mention must be made of its single-centre nature&#44; with a limited number of patients who were moreover selected on the grounds of a good basal status &#40;both mental and physical&#41;&#44; and with low comorbidity as previously described<a class="elsevierStyleCrossRef" href="#bib0350"><span class="elsevierStyleSup">34</span></a> and also seen in similar studies&#46;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">16&#44;28&#44;35&#44;36</span></a> Furthermore&#44; we did not record the limitation of therapeutic effort rates&#44; which could have been interesting for better analysis of the data&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">In conclusion&#44; we found that patients over 75 years of age with prolonged admission to the ICU suffer high mortality both in the ICU and in hospital&#44; and such mortality is moreover greater than in patients requiring shorter stays in intensive care&#46; Nevertheless&#44; the survivors of prolonged admission to the ICU show a high survival rate after one year&#8211;though functional status is poorer than before admission to the ICU&#44; despite slight improvement during the year of follow-up&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conflict of interest</span><p id="par0170" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres678045"
          "titulo" => "Abstract"
          "secciones" => array:7 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Objective"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Design"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Setting"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Patients"
            ]
            4 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Primary variables of interest"
            ]
            5 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Results"
            ]
            6 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec684017"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres678046"
          "titulo" => "Resumen"
          "secciones" => array:7 [
            0 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Objetivo"
            ]
            1 => array:2 [
              "identificador" => "abst0045"
              "titulo" => "Dise&#241;o"
            ]
            2 => array:2 [
              "identificador" => "abst0050"
              "titulo" => "&#193;mbito"
            ]
            3 => array:2 [
              "identificador" => "abst0055"
              "titulo" => "Pacientes"
            ]
            4 => array:2 [
              "identificador" => "abst0060"
              "titulo" => "Variables de inter&#233;s principales"
            ]
            5 => array:2 [
              "identificador" => "abst0065"
              "titulo" => "Resultados"
            ]
            6 => array:2 [
              "identificador" => "abst0070"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec684016"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Patients and methods"
          "secciones" => array:1 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Statistical analysis"
            ]
          ]
        ]
        6 => array:3 [
          "identificador" => "sec0020"
          "titulo" => "Results"
          "secciones" => array:1 [
            0 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Follow-up after one year"
            ]
          ]
        ]
        7 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflict of interest"
        ]
        9 => array:2 [
          "identificador" => "xack228635"
          "titulo" => "Acknowledgements"
        ]
        10 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2015-03-20"
    "fechaAceptado" => "2015-08-07"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec684017"
          "palabras" => array:5 [
            0 => "Elderly"
            1 => "Prognosis"
            2 => "Long-term outcome"
            3 => "Health-related quality of life"
            4 => "Critical care"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec684016"
          "palabras" => array:5 [
            0 => "Ancianos"
            1 => "Pron&#243;stico"
            2 => "Resultado a largo plazo"
            3 => "Calidad de vida relacionada con la salud"
            4 => "Cuidados intensivos"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate mortality and functional status at one year of follow-up in patients &#62;75 years of age who survive Intensive Care Unit &#40;ICU&#41; admission of over 14 days&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Design</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A prospective observational study was carried out&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Setting</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A Spanish medical&#8211;surgical ICU&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Patients</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Patients over 75 years of age admitted to the ICU&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Primary variables of interest</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">ICU admission&#58; demographic data&#44; baseline functional status &#40;Barthel index&#41;&#44; baseline mental status &#40;Red Cross scale of mental incapacity&#41;&#44; severity of illness &#40;APACHE II and SOFA&#41;&#44; stay and mortality&#46; One-year follow-up&#58; hospital stay and mortality&#44; functional and mental status&#44; and one-year follow-up mortality&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Results</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A total of 176 patients were included&#44; of which 22 had a stay of over 14 days&#46; Patients with prolonged stay did not show more ICU mortality than those with a shorter stay in the ICU &#40;40&#46;9&#37; vs 25&#46;3&#37; respectively&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;12&#41;&#44; although their hospital &#40;63&#46;6&#37; vs 33&#46;8&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;01&#41; and one-year follow-up mortality were higher &#40;68&#46;2&#37; vs 41&#46;2&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41;&#46; Among the survivors&#44; one-year mortality proved similar &#40;87&#46;5&#37; vs 90&#46;6&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;57&#41;&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">These patients presented significantly greater impairment of functional status at hospital discharge than the patients with a shorter ICU stay&#44; and this difference persisted after three months&#46; The levels of independence at one-year follow-up were never similar to baseline&#46; No such findings were observed in relation to mental status&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Patients over 75 years of age with a ICU stay of more than 14 days have high hospital and one-year follow-up mortality&#46; Patients who survive to hospital admission did not show greater mortality&#44; though their functional dependency was greater&#46;</p></span>"
        "secciones" => array:7 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objective"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Design"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Setting"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Patients"
          ]
          4 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Primary variables of interest"
          ]
          5 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Results"
          ]
          6 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Objetivo</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Determinar la mortalidad y situaci&#243;n funcional al a&#241;o de los pacientes mayores de 75 a&#241;os con estancia en una unidad de cuidados intensivos &#40;UCI&#41; mayor de 14 d&#237;as&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Dise&#241;o</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Estudio prospectivo observacional&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">&#193;mbito</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">UCI m&#233;dico-quir&#250;rgica espa&#241;ola&#46;</p></span> <span id="abst0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Pacientes</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Pacientes mayores de 75 a&#241;os ingresados en UCI&#46;</p></span> <span id="abst0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Variables de inter&#233;s principales</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Ingreso en UCI&#58; datos demogr&#225;ficos&#44; estado funcional basal &#40;&#237;ndice de Barthel&#41;&#44; estado mental basal &#40;Escala de incapacidad mental de la Cruz Roja&#41;&#44; gravedad de la enfermedad &#40;APACHE II y SOFA&#41;&#44; mortalidad y estancia&#46; Seguimiento al a&#241;o&#58; estancia&#47;mortalidad hospitalaria&#44; situaci&#243;n funcional y mental y mortalidad al a&#241;o&#46;</p></span> <span id="abst0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Incluimos 176 pacientes&#44; 22 con una estancia mayor de 14 d&#237;as&#46; Los pacientes con estancias prolongadas no presentaron mayor mortalidad en UCI que los de menor estancia &#40;40&#44;9&#37; vs&#46; 25&#44;3&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;12&#41;&#44; aunque su mortalidad hospitalaria &#40;63&#44;6&#37; vs&#46; 33&#44;8&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41; y al a&#241;o &#40;68&#44;2&#37; vs&#46; 41&#44;2&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41; fue superior&#46; Entre los supervivientes la supervivencia al a&#241;o fue similar &#40;87&#44;5&#37; vs&#46; 90&#44;6&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;57&#41;&#46;</p><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Estos pacientes presentaron un deterioro en su situaci&#243;n funcional al alta hospitalaria significativamente mayor que los de corta estancia&#44; diferencia que se mantuvo a los 3 meses&#46; Nunca llegaron a alcanzar niveles de independencia previos al ingreso durante el a&#241;o&#46; Estos hallazgos no se observaron a nivel mental&#46;</p></span> <span id="abst0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Conclusiones</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Los pacientes mayores de 75 a&#241;os con estancia en UCI mayor de 14 d&#237;as presentan una mortalidad hospitalaria y al a&#241;o elevada&#46; Los pacientes que logran ser dados de alta del hospital no presentan mayor mortalidad&#44; aunque s&#237; presentan mayor grado de dependencia funcional&#46;</p></span>"
        "secciones" => array:7 [
          0 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0045"
            "titulo" => "Dise&#241;o"
          ]
          2 => array:2 [
            "identificador" => "abst0050"
            "titulo" => "&#193;mbito"
          ]
          3 => array:2 [
            "identificador" => "abst0055"
            "titulo" => "Pacientes"
          ]
          4 => array:2 [
            "identificador" => "abst0060"
            "titulo" => "Variables de inter&#233;s principales"
          ]
          5 => array:2 [
            "identificador" => "abst0065"
            "titulo" => "Resultados"
          ]
          6 => array:2 [
            "identificador" => "abst0070"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0020">Please cite this article as&#58; Pintado MC&#44; Villa P&#44; Luj&#225;n J&#44; Trascasa M&#44; Molina R&#44; Gonz&#225;lez-Garc&#237;a N&#44; et al&#46; Mortalidad y estado funcional al a&#241;o de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos&#46; Med Intensiva&#46; 2016&#59;40&#58;289&#8211;297&#46;</p>"
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2115
            "Ancho" => 2781
            "Tamanyo" => 243892
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Flowchart&#46; The figure shows the flowchart of the patients included in the study&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2076
            "Ancho" => 2372
            "Tamanyo" => 219523
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">Functional status in the course of the study&#46; The figures show the evolution of functional status as scored with the Barthel index in the course of the study in the two groups&#58; prolonged admission and short stay&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2825
            "Ancho" => 2045
            "Tamanyo" => 300989
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">Mental status&#46; The figures show the evolution of mental status as scored with the Red Cross Psychic Disability scale in the course of the study in the two groups&#58; prolonged admission and short stay&#46; No significant differences were found on comparing the different moments of the study &#40;basal&#44; hospital discharge and follow-up during one year&#41; in each group or between groups&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0105" class="elsevierStyleSimplePara elsevierViewall">The results are presented as number and percentage&#44; except&#58;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Short stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>154&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Prolonged stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>-Value&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Age</span><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#46;82<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">79&#46;27<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#46;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Age group</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62;75&#8211;80 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70 &#40;45&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;68&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>81&#8211;85 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54 &#40;35&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;27&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62;85 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">30 &#40;19&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Gender&#58; male&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">75 &#40;48&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;59&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Charlson score<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;67<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;32<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Comorbidity</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Low&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">79 &#40;51&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;54&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Moderate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41 &#40;26&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;36&#46;40&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>High&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34 &#40;22&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Barthel index<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;00 &#40;80&#46;00&#8211;100&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&#46;00 &#40;90&#46;00&#8211;100&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;42&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Degree of functional dependency</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;76&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Independent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68 &#40;49&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;54&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Slight dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54 &#40;39&#46;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;40&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Moderate dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;7&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Severe dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;2&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Total dependency&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Functional dependency &#40;BI &#60; 60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;10&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;70&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Red Cross psychic disability scale</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Completely normal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">97 &#40;71&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;77&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Slight disorientation in time&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;18&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;13&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Disorientation in time&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;9&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Reason for admission</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cardiovascular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">92 &#40;59&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;13&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Infectious&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;18&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;59&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Respiratory&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;3&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;13&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Resuscitated cardiac arrest&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;6&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Neurological&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;3&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Intoxications&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Digestive&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Surgery&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;3&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Techniques&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>APACHE II<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16&#46;50 &#40;11&#46;00&#8211;24&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#46;00 &#40;19&#46;00&#8211;28&#46;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>SOFA<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;00 &#40;1&#46;00&#8211;8&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;00 &#40;7&#46;00&#8211;12&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1112755.png"
              ]
            ]
          ]
          "notaPie" => array:2 [
            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Median &#40;percentile<span class="elsevierStyleInf">25</span>&#8211;percentile<span class="elsevierStyleInf">75</span>&#41;&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">Basal characteristics of the patients over 75 years of age admitted to the ICU according to the duration of stay&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">The results are presented as number and percentage&#44; except&#58;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Short stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>154&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Prolonged stay &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>-Value&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Presence of multiorgan failure&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">56 &#40;36&#46;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;100&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Mechanical ventilation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">57 &#40;37&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;100&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Vasoactive drug support&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">86 &#40;55&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;100&#46;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Renal replacement therapy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;1&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;18&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Poorer SOFA score<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;00 &#40;2&#46;00&#8211;10&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;00 &#40;8&#46;75&#8211;12&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Stay in ICU &#40;days&#41;<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;00 &#40;2&#46;00&#8211;5&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">32&#46;00 &#40;17&#46;00&#8211;45&#46;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Hospital stay &#40;days&#41;<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;00 &#40;6&#46;00&#8211;16&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#46;00 &#40;27&#46;00&#8211;71&#46;00&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Mortality in ICU&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">39 &#40;25&#46;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;40&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Mortality in hospital&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52 &#40;33&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;63&#46;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1112756.png"
              ]
            ]
          ]
          "notaPie" => array:1 [
            0 => array:3 [
              "identificador" => "tblfn0015"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Median &#40;percentile<span class="elsevierStyleInf">25</span>&#8211;percentile<span class="elsevierStyleInf">75</span>&#41;&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0110" class="elsevierStyleSimplePara elsevierViewall">Evolution of the patients during admission to the ICU according to the duration of stay&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:36 [
            0 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The impact of critical illness on perceived health-related quality of life during ICU treatment&#44; hospital stay&#44; and after hospital discharge&#58; a long-term follow-up study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;G&#46; Hofhuis"
                            1 => "P&#46;E&#46; Spronk"
                            2 => "H&#46;F&#46; van Stel"
                            3 => "G&#46;J&#46; Schrijvers"
                            4 => "J&#46;H&#46; Rommes"
                            5 => "J&#46; Bakker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.07-1217"
                      "Revista" => array:7 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2008"
                        "volumen" => "133"
                        "paginaInicial" => "377"
                        "paginaFinal" => "385"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17925419"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673612602402"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Persistent organ dysfunction plus death&#58; a novel&#44; composite outcome measure for critical care trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;K&#46; Heyland"
                            1 => "J&#46; Muscedere"
                            2 => "J&#46; Drover"
                            3 => "X&#46; Jiang"
                            4 => "A&#46;G&#46; Day"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc10110"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "R98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21418560"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Determinants of long-term survival after intensive care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46;A&#46; Williams"
                            1 => "G&#46;J&#46; Dobb"
                            2 => "J&#46;C&#46; Finn"
                            3 => "M&#46;W&#46; Knuiman"
                            4 => "E&#46; Geelhoed"
                            5 => "K&#46;Y&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e318170a405"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "1523"
                        "paginaFinal" => "1530"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18434893"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Post-Intensive Care Unit mortality and related prognostic factors in a cohort of critically ill patients with multi-organ dysfunction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "V&#46;A&#46; Hortiguela-Martin"
                            1 => "M&#46; Sanchez-Casado"
                            2 => "S&#46; Rodriguez-Villar"
                            3 => "M&#46; Quintana-D&#237;az"
                            4 => "C&#46; Marco-Shulke"
                            5 => "V&#46; G&#243;mez-Tello"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2013"
                        "volumen" => "140"
                        "paginaInicial" => "479"
                        "paginaFinal" => "486"
                        "itemHostRev" => array:3 [
                          "pii" => "S095461111300173X"
                          "estado" => "S300"
                          "issn" => "09546111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mortality after hospital discharge in ICU patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Brinkman"
                            1 => "E&#46; de Jonge"
                            2 => "A&#46; Abu-Hanna"
                            3 => "M&#46;S&#46; Arbous"
                            4 => "D&#46;W&#46; de Lange"
                            5 => "N&#46;F&#46; de Keizer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e31827ca4e1"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2013"
                        "volumen" => "41"
                        "paginaInicial" => "1229"
                        "paginaFinal" => "1236"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23591209"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term mortality outcome associated with prolonged admission to the ICU"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;B&#46; Laupland"
                            1 => "A&#46;W&#46; Kirkpatrick"
                            2 => "J&#46;B&#46; Kortbeek"
                            3 => "D&#46;J&#46; Zuege"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.129.4.954"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2006"
                        "volumen" => "129"
                        "paginaInicial" => "954"
                        "paginaFinal" => "959"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16608944"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes of health-related quality of life in critically ill octogenarians&#58; a follow-up study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;G&#46; Hofhuis"
                            1 => "H&#46;F&#46; van Stel"
                            2 => "A&#46;J&#46; Schrijvers"
                            3 => "J&#46;H&#46; Rommes"
                            4 => "P&#46;E&#46; Spronk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.10-0803"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2011"
                        "volumen" => "140"
                        "paginaInicial" => "1473"
                        "paginaFinal" => "1483"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21960698"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome and mortality risk factors in long-term treated ICU patients&#58; a retrospective analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Bickenbach"
                            1 => "M&#46; Fries"
                            2 => "S&#46; Rex"
                            3 => "C&#46; Stitz"
                            4 => "N&#46; Heussen"
                            5 => "R&#46; Rossaint"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Minerva Anestesiol"
                        "fecha" => "2011"
                        "volumen" => "77"
                        "paginaInicial" => "427"
                        "paginaFinal" => "438"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21483387"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome&#44; functional autonomy&#44; and quality of life of elderly patients with a long-term intensive care unit stay"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "L&#46; Montuclard"
                            1 => "Garrouste-Org"
                            2 => "J&#46;F&#46; Timsit"
                            3 => "B&#46; Misset"
                            4 => "B&#46; de Jonghe"
                            5 => "J&#46; Carlet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "28"
                        "paginaInicial" => "3389"
                        "paginaFinal" => "3395"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11057791"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome and functional capacity after prolonged intensive care unit stay"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;G&#46; Delle"
                            1 => "B&#46; Meyer"
                            2 => "S&#46; Bauer"
                            3 => "M&#46; Nikfardjam"
                            4 => "G&#46; Heinz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00508-006-0616-z"
                      "Revista" => array:6 [
                        "tituloSerie" => "Wien Klin Wochenschr"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "390"
                        "paginaFinal" => "396"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16865643"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival and quality of life after a long-term intensive care stay"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46; Isgro"
                            1 => "J&#46;A&#46; Skuras"
                            2 => "A&#46;H&#46; Kiessling"
                            3 => "A&#46; Lehmann"
                            4 => "W&#46; Saggau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1055/s-2002-26693"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorac Cardiovasc Surg"
                        "fecha" => "2002"
                        "volumen" => "50"
                        "paginaInicial" => "95"
                        "paginaFinal" => "99"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11981710"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Morbidity&#44; mortality&#44; and quality-of-life outcomes of patients requiring &#8805;14 days of mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Combes"
                            1 => "M&#46;A&#46; Costa"
                            2 => "J&#46;L&#46; Trouillet"
                            3 => "J&#46; Baudot"
                            4 => "M&#46; Mokhtari"
                            5 => "C&#46; Gibert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000065188.87029.C3"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2003"
                        "volumen" => "31"
                        "paginaInicial" => "1373"
                        "paginaFinal" => "1381"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12771605"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term outcome of long stay ICU and HDU patients in a New Zealand Hospital"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;P&#46; Carden"
                            1 => "J&#46;W&#46; Graham"
                            2 => "S&#46; McLennan"
                            3 => "L&#46;A&#46; Celi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Shock"
                        "fecha" => "2008"
                        "volumen" => "11"
                        "paginaInicial" => "26"
                        "paginaFinal" => "34"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23766668"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short- and long-term survival of nonsurgical intensive care patients and its relation to diagnosis&#44; severity of disease&#44; age and comorbidities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;A&#46; Kaufmann"
                            1 => "K&#46;H&#46; Smolle"
                            2 => "G&#46;J&#46; Krejs"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Aging Sci"
                        "fecha" => "2009"
                        "volumen" => "2"
                        "paginaInicial" => "240"
                        "paginaFinal" => "248"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20021418"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The eldicus prospective&#44; observational study of triage decision making in European intensive care units&#46; Part II&#58; intensive care benefit for the elderly"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;L&#46; Sprung"
                            1 => "A&#46; Artigas"
                            2 => "J&#46; Kesecioglu"
                            3 => "A&#46; Pezzi"
                            4 => "J&#46; Wiis"
                            5 => "R&#46; Pirracchio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e318232d6b0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2012"
                        "volumen" => "40"
                        "paginaInicial" => "132"
                        "paginaFinal" => "138"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22001580"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Decision-making process&#44; outcome&#44; and 1-year quality of life of octogenarians referred for intensive care unit admission"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Garrouste-Org"
                            1 => "J&#46;F&#46; Timsit"
                            2 => "L&#46; Montuclard"
                            3 => "A&#46; Colvez"
                            4 => "O&#46; Gattolliat"
                            5 => "F&#46; Philippart"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00134-006-0169-7"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "2006"
                        "volumen" => "32"
                        "paginaInicial" => "1045"
                        "paginaFinal" => "1051"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16791667"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Functional status and quality of life 12 months after discharge from a medical ICU in healthy elderly patients&#58; a prospective observational study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Sacanella"
                            1 => "J&#46;M&#46; Perez-Castejon"
                            2 => "J&#46;M&#46; Nicolas"
                            3 => "F&#46; Masanes"
                            4 => "M&#46; Navarro"
                            5 => "P&#46; Castro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc10121"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "R105"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21443796"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Five-year survival and prognostic factors in a cohort of hospitalized nonagenarians"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Conde-Martel"
                            1 => "M&#46; Hemmersbach-Miller"
                            2 => "J&#46; Marchena-Gomez"
                            3 => "P&#46; Saavedra-Santana"
                            4 => "P&#46; Betancor-Leon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ejim.2012.02.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Intern Med"
                        "fecha" => "2012"
                        "volumen" => "23"
                        "paginaInicial" => "513"
                        "paginaFinal" => "518"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22863427"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and prognosis of patients with very long stay in an Intensive Care Unit"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46;L&#46; Santana"
                            1 => "M&#46; Sanchez-Palacios"
                            2 => "M&#46;E&#46; Hernandez"
                            3 => "R&#46;P&#46; Eugenio"
                            4 => "A&#46; Villanueva-Hernandez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Intensiva"
                        "fecha" => "2008"
                        "volumen" => "32"
                        "paginaInicial" => "157"
                        "paginaFinal" => "162"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18413119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is it &#8216;worthwhile&#8217; to continue treating patients with a prolonged stay &#40;&#62;14 days&#41; in the ICU&#63; An economic evaluation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;K&#46; Heyland"
                            1 => "E&#46; Konopad"
                            2 => "T&#46;W&#46; Noseworthy"
                            3 => "R&#46; Johnston"
                            4 => "A&#46; Gafni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1998"
                        "volumen" => "114"
                        "paginaInicial" => "192"
                        "paginaFinal" => "198"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9674469"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Disability in activities of daily living&#44; depression&#44; and quality of life among older medical ICU survivors&#58; a prospective cohort study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;T&#46; Vest"
                            1 => "T&#46;E&#46; Murphy"
                            2 => "K&#46;L&#46; Araujo"
                            3 => "M&#46;A&#46; Pisani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1477-7525-9-9"
                      "Revista" => array:5 [
                        "tituloSerie" => "Health Qual Life Outcomes"
                        "fecha" => "2011"
                        "volumen" => "9"
                        "paginaInicial" => "9"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21294911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A new method of classifying prognostic comorbidity in longitudinal studies&#58; development and validation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;E&#46; Charlson"
                            1 => "P&#46; Pompei"
                            2 => "K&#46;L&#46; Ales"
                            3 => "C&#46;R&#46; MacKenzie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Chronic Dis"
                        "fecha" => "1987"
                        "volumen" => "40"
                        "paginaInicial" => "373"
                        "paginaFinal" => "383"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3558716"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Functional evaluation&#58; the Barthel Index"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46;I&#46; Mahoney"
                            1 => "D&#46;W&#46; Barthel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Md State Med J"
                        "fecha" => "1965"
                        "volumen" => "14"
                        "paginaInicial" => "61"
                        "paginaFinal" => "65"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5832033"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ayuda a domicilio&#46; Aspectos m&#233;dicos en geriatr&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Guill&#233;n Llera"
                            1 => "A&#46; Garc&#237;a Ant&#243;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Esp Gerontol"
                        "fecha" => "1972"
                        "volumen" => "7"
                        "paginaInicial" => "339"
                        "paginaFinal" => "346"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0305"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "APACHE II&#58; a severity of disease classification system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46;A&#46; Knaus"
                            1 => "E&#46;A&#46; Draper"
                            2 => "D&#46;P&#46; Wagner"
                            3 => "J&#46;E&#46; Zimmerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "1985"
                        "volumen" => "13"
                        "paginaInicial" => "818"
                        "paginaFinal" => "829"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3928249"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0310"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of the SOFA score to assess the incidence of organ dysfunction&#47;failure in intensive care units&#58; results of a multicenter&#44; prospective study&#46; Working group on &#171;sepsis-related problems&#187; of the European Society of Intensive Care Medicine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;L&#46; Vincent"
                            1 => "A&#46; de Mendonca"
                            2 => "F&#46; Cantraine"
                            3 => "R&#46; Moreno"
                            4 => "J&#46; Takala"
                            5 => "P&#46;M&#46; Suter"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "1998"
                        "volumen" => "26"
                        "paginaInicial" => "1793"
                        "paginaFinal" => "1800"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9824069"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0315"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term survival&#44; quality of life&#44; and quality-adjusted life-years among critically ill elderly patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Kaarlola"
                            1 => "M&#46; Tallgren"
                            2 => "V&#46; Pettila"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000227656.31911.2E"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2006"
                        "volumen" => "34"
                        "paginaInicial" => "2120"
                        "paginaFinal" => "2126"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16763517"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0320"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Variability of intensive care admission decisions for the very elderly"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Boumendil"
                            1 => "D&#46;C&#46; Angus"
                            2 => "A&#46;L&#46; Guitonneau"
                            3 => "A&#46;M&#46; Menn"
                            4 => "C&#46; Ginsburg"
                            5 => "K&#46; Takun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0034387"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2012"
                        "volumen" => "7"
                        "paginaInicial" => "e34387"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22509296"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0325"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acceptable long-term outcome in elderly intensive care unit patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;A&#46; Schroder"
                            1 => "J&#46;B&#46; Poulsen"
                            2 => "A&#46; Perner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dan Med Bull"
                        "fecha" => "2011"
                        "volumen" => "58"
                        "paginaInicial" => "A4297"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21722543"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0330"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in patients aged 80 or over after ICU discharge"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Tabah"
                            1 => "F&#46; Philippart"
                            2 => "J&#46;F&#46; Timsit"
                            3 => "V&#46; Willems"
                            4 => "A&#46; Francais"
                            5 => "A&#46; Leplege"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc8231"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2010"
                        "volumen" => "14"
                        "paginaInicial" => "R2"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20064197"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0335"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cognitive&#44; functional&#44; and quality-of-life outcomes of patients aged 80 and older who survived at least 1 year after planned or unplanned surgery or medical intensive care treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46;E&#46; De Rooij"
                            1 => "A&#46;C&#46; Govers"
                            2 => "J&#46;C&#46; Korevaar"
                            3 => "A&#46;W&#46; Giesbers"
                            4 => "M&#46; Levi"
                            5 => "E&#46; de Jonge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1532-5415.2008.01671.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Geriatr Soc"
                        "fecha" => "2008"
                        "volumen" => "56"
                        "paginaInicial" => "816"
                        "paginaFinal" => "822"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18384589"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0340"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Geriatric conditions in acutely hospitalized older patients&#58; prevalence and one-year survival and functional decline"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;M&#46; Buurman"
                            1 => "J&#46;G&#46; Hoogerduijn"
                            2 => "R&#46;J&#46; de Haan"
                            3 => "A&#46; Abu-Hanna"
                            4 => "A&#46;M&#46; Lagaay"
                            5 => "H&#46;J&#46; Verhaar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0026951"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2011"
                        "volumen" => "6"
                        "paginaInicial" => "e26951"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22110598"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0345"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term outcome of critically ill elderly patients requiring intensive care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46; Chelluri"
                            1 => "M&#46;R&#46; Pinsky"
                            2 => "M&#46;P&#46; Donahoe"
                            3 => "A&#46; Grenvik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "1993"
                        "volumen" => "269"
                        "paginaInicial" => "3119"
                        "paginaFinal" => "3123"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8505814"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0350"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and outcomes of elderly patients refused to ICU"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;C&#46; Pintado"
                            1 => "P&#46; Villa"
                            2 => "N&#46; Gonzalez-Garcia"
                            3 => "J&#46; Lujan"
                            4 => "R&#46; Molina"
                            5 => "M&#46; Trascasa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Sci World J"
                        "fecha" => "2013"
                        "volumen" => "2013"
                        "paginaInicial" => "590837"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0355"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reasons for refusal of admission to intensive care and impact on mortality"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Iapichino"
                            1 => "D&#46; Corbella"
                            2 => "C&#46; Minelli"
                            3 => "G&#46;H&#46; Mills"
                            4 => "A&#46; Artigas"
                            5 => "D&#46;L&#46; Edbooke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00134-010-1933-2"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "2010"
                        "volumen" => "36"
                        "paginaInicial" => "1772"
                        "paginaFinal" => "1779"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20533023"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0360"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of triage decisions for intensive care admission"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;L&#46; Sprung"
                            1 => "D&#46; Geber"
                            2 => "L&#46;A&#46; Eidelman"
                            3 => "M&#46; Baras"
                            4 => "R&#46; Pizov"
                            5 => "A&#46; Nimrod"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "27"
                        "paginaInicial" => "1073"
                        "paginaFinal" => "1079"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10397207"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
    "agradecimientos" => array:1 [
      0 => array:4 [
        "identificador" => "xack228635"
        "titulo" => "Acknowledgements"
        "texto" => "<p id="par0175" class="elsevierStylePara elsevierViewall">Thanks are due to all the patients and personnel members who made this study possible&#46;</p>"
        "vista" => "all"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735727/0000004000000005/v1_201606250031/S2173572716300170/v1_201606250031/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/21735727/0000004000000005/v1_201606250031/S2173572716300170/v1_201606250031/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572716300170?idApp=WMIE"
]
Article information
ISSN: 21735727
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 10 10 20
2024 October 60 47 107
2024 September 92 36 128
2024 August 121 47 168
2024 July 83 22 105
2024 June 97 51 148
2024 May 59 31 90
2024 April 110 33 143
2024 March 77 28 105
2024 February 63 40 103
2024 January 59 34 93
2023 December 51 43 94
2023 November 60 21 81
2023 October 74 49 123
2023 September 69 47 116
2023 August 49 34 83
2023 July 75 31 106
2023 June 45 22 67
2023 May 61 30 91
2023 April 63 29 92
2023 March 65 36 101
2023 February 52 40 92
2023 January 53 32 85
2022 December 57 46 103
2022 November 70 39 109
2022 October 112 41 153
2022 September 106 44 150
2022 August 98 44 142
2022 July 88 38 126
2022 June 56 21 77
2022 May 105 34 139
2022 April 94 57 151
2022 March 61 60 121
2022 February 47 39 86
2022 January 42 42 84
2021 December 45 46 91
2021 November 57 48 105
2021 October 114 85 199
2021 September 52 43 95
2021 August 53 54 107
2021 July 29 53 82
2021 June 43 29 72
2021 May 75 56 131
2021 April 175 99 274
2021 March 118 51 169
2021 February 68 51 119
2021 January 74 68 142
2020 December 72 40 112
2020 November 69 20 89
2020 October 63 39 102
2020 September 46 29 75
2020 August 58 25 83
2020 July 57 34 91
2020 June 61 25 86
2020 May 58 19 77
2020 April 60 30 90
2020 March 46 30 76
2020 February 124 41 165
2020 January 57 26 83
2019 December 64 33 97
2019 November 81 34 115
2019 October 79 26 105
2019 September 53 34 87
2019 August 50 35 85
2019 July 48 25 73
2019 June 46 31 77
2019 May 102 41 143
2019 April 48 37 85
2019 March 51 38 89
2019 February 73 37 110
2019 January 59 48 107
2018 December 75 39 114
2018 November 231 65 296
2018 October 95 29 124
2018 September 40 12 52
2018 August 24 8 32
2018 July 30 10 40
2018 June 33 10 43
2018 May 21 6 27
2018 April 34 11 45
2018 March 22 5 27
2018 February 17 7 24
2018 January 34 7 41
2017 December 38 8 46
2017 November 32 8 40
2017 October 36 10 46
2017 September 37 11 48
2017 August 25 12 37
2017 July 25 12 37
2017 June 46 10 56
2017 May 51 14 65
2017 April 57 28 85
2017 March 38 9 47
2017 February 29 22 51
2017 January 21 9 30
2016 December 40 22 62
2016 November 41 26 67
2016 October 55 0 55
2016 September 38 0 38
2016 August 1 0 1
Show all

Follow this link to access the full text of the article

Idiomas
Medicina Intensiva (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?