was read the article
array:25 [ "pii" => "S2173572718301024" "issn" => "21735727" "doi" => "10.1016/j.medine.2017.07.004" "estado" => "S300" "fechaPublicacion" => "2018-06-01" "aid" => "1090" "copyright" => "Elsevier España, S.L.U. and SEMICYUC" "copyrightAnyo" => "2017" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Med Intensiva. 2018;42:266-73" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1020 "formatos" => array:3 [ "EPUB" => 201 "HTML" => 381 "PDF" => 438 ] ] "Traduccion" => array:1 [ "en" => array:19 [ "pii" => "S0210569117302140" "issn" => "02105691" "doi" => "10.1016/j.medin.2017.07.002" "estado" => "S300" "fechaPublicacion" => "2018-06-01" "aid" => "1090" "copyright" => "Elsevier España, S.L.U. y SEMICYUC" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Med Intensiva. 2018;42:266-73" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3391 "formatos" => array:3 [ "EPUB" => 211 "HTML" => 1960 "PDF" => 1220 ] ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>" "titulo" => "Antimicrobial stewardship programme in critical care medicine: A prospective interventional study" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "266" "paginaFinal" => "273" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Implantación de un programa de optimización de antimicrobianos en el paciente crítico: Estudio de intervención" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Ruiz, P. Ramirez, M. Gordon, E. Villarreal, J. Frasquet, J.L. Poveda-Andres, M. Salavert-Lletí, A. Catellanos" "autores" => array:8 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Ruiz" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Ramirez" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Gordon" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Villarreal" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Frasquet" ] 5 => array:2 [ "nombre" => "J.L." "apellidos" => "Poveda-Andres" ] 6 => array:2 [ "nombre" => "M." "apellidos" => "Salavert-Lletí" ] 7 => array:2 [ "nombre" => "A." "apellidos" => "Catellanos" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S217357271830105X" "doi" => "10.1016/j.medine.2017.10.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357271830105X?idApp=WMIE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569117302140?idApp=WMIE" "url" => "/02105691/0000004200000005/v1_201805290410/S0210569117302140/v1_201805290410/en/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2173572718300870" "issn" => "21735727" "doi" => "10.1016/j.medine.2018.04.003" "estado" => "S300" "fechaPublicacion" => "2018-06-01" "aid" => "1112" "copyright" => "Elsevier España, S.L.U. and SEMICYUC" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Med Intensiva. 2018;42:274-82" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1570 "formatos" => array:3 [ "EPUB" => 171 "HTML" => 734 "PDF" => 665 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original</span>" "titulo" => "Results and functional outcomes of acute ischemic stroke patients who underwent mechanical thrombectomy admitted to intensive care unit" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "274" "paginaFinal" => "282" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Resultados y evolución funcional de pacientes críticos con ictus isquémico sometidos a trombectomía mecánica" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1313 "Ancho" => 2083 "Tamanyo" => 107301 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Scores of the modified Rankin scale (mRS) one year after the ischemic event. The percentage of patients with scores between 0 and 6 on the mRS are shown: 0<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>no symptoms; 1<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>no major disability (able to carry out routine activities and duties); 2<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>mild disability (unable to carry out some previous activities, but able to care for own interests and concerns without help); 3<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>moderate disability (symptoms that significantly restrict lifestyle or impede full autonomy: some help required); 4<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>moderately severe disability (symptoms that clearly impede independent living, though without the need for continuous care: unable to attend personal needs without help); 5<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>severe disability (totally dependent: needs constant attention, day and night); 6<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>death.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L. Viña Soria, L. Martín Iglesias, L. López Amor, I. Astola Hidalgo, R. Rodríguez García, L. Forcelledo Espina, J.A. Gonzalo Guerra, S. de Cima Iglesias, E. Murias Quintana, P. Vega Valdés, S. Calleja Puerta, D. Escudero Augusto" "autores" => array:12 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Viña Soria" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Martín Iglesias" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "López Amor" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Astola Hidalgo" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Rodríguez García" ] 5 => array:2 [ "nombre" => "L." "apellidos" => "Forcelledo Espina" ] 6 => array:2 [ "nombre" => "J.A." "apellidos" => "Gonzalo Guerra" ] 7 => array:2 [ "nombre" => "S." "apellidos" => "de Cima Iglesias" ] 8 => array:2 [ "nombre" => "E." "apellidos" => "Murias Quintana" ] 9 => array:2 [ "nombre" => "P." "apellidos" => "Vega Valdés" ] 10 => array:2 [ "nombre" => "S." "apellidos" => "Calleja Puerta" ] 11 => array:2 [ "nombre" => "D." "apellidos" => "Escudero Augusto" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210569117302413" "doi" => "10.1016/j.medin.2017.07.012" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569117302413?idApp=WMIE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572718300870?idApp=WMIE" "url" => "/21735727/0000004200000005/v1_201805310404/S2173572718300870/v1_201805310404/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S217357271830105X" "issn" => "21735727" "doi" => "10.1016/j.medine.2017.10.011" "estado" => "S300" "fechaPublicacion" => "2018-06-01" "aid" => "1135" "copyright" => "Elsevier España, S.L.U. and SEMICYUC" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Intensiva. 2018;42:263-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1630 "formatos" => array:3 [ "EPUB" => 188 "HTML" => 950 "PDF" => 492 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>" "titulo" => "Antimicrobial stewardship program in critical care medicine: What is going on? Who gives more?" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "263" "paginaFinal" => "265" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Programas de optimización antibiótica en medicina crítica. ¿Qué está ocurriendo? ¿Quién da más?" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Zaragoza Crespo, A.C. Cercos LLetí" "autores" => array:2 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Zaragoza Crespo" ] 1 => array:2 [ "nombre" => "A.C." "apellidos" => "Cercos LLetí" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0210569117302140" "doi" => "10.1016/j.medin.2017.07.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569117302140?idApp=WMIE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357271830105X?idApp=WMIE" "url" => "/21735727/0000004200000005/v1_201805310404/S217357271830105X/v1_201805310404/en/main.assets" ] "asociados" => array:1 [ 0 => array:19 [ "pii" => "S217357271830105X" "issn" => "21735727" "doi" => "10.1016/j.medine.2017.10.011" "estado" => "S300" "fechaPublicacion" => "2018-06-01" "aid" => "1135" "copyright" => "Elsevier España, S.L.U. and SEMICYUC" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Intensiva. 2018;42:263-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1630 "formatos" => array:3 [ "EPUB" => 188 "HTML" => 950 "PDF" => 492 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>" "titulo" => "Antimicrobial stewardship program in critical care medicine: What is going on? Who gives more?" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "263" "paginaFinal" => "265" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Programas de optimización antibiótica en medicina crítica. ¿Qué está ocurriendo? ¿Quién da más?" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Zaragoza Crespo, A.C. Cercos LLetí" "autores" => array:2 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Zaragoza Crespo" ] 1 => array:2 [ "nombre" => "A.C." "apellidos" => "Cercos LLetí" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0210569117302140" "doi" => "10.1016/j.medin.2017.07.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210569117302140?idApp=WMIE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357271830105X?idApp=WMIE" "url" => "/21735727/0000004200000005/v1_201805310404/S217357271830105X/v1_201805310404/en/main.assets" ] ] "en" => array:15 [ "idiomaDefecto" => true "titulo" => "Antimicrobial stewardship programme in critical care medicine: A prospective interventional study" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "266" "paginaFinal" => "273" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Ruiz, P. Ramirez, M. Gordon, E. Villarreal, J. Frasquet, J.L. Poveda-Andres, M. Salavert-Lletí, A. Catellanos" "autores" => array:8 [ 0 => array:3 [ "nombre" => "J." "apellidos" => "Ruiz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "P." "apellidos" => "Ramirez" "email" => array:1 [ 0 => "ramirez_pau@gva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "M." "apellidos" => "Gordon" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "E." "apellidos" => "Villarreal" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "J." "apellidos" => "Frasquet" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "J.L." "apellidos" => "Poveda-Andres" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 6 => array:3 [ "nombre" => "M." "apellidos" => "Salavert-Lletí" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] 7 => array:3 [ "nombre" => "A." "apellidos" => "Catellanos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Intensive Care Unit, Hospital Universitario y Politecnico La Fe, Valencia, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Microbiology Department, Hospital Universitario y Politecnico La Fe, Valencia, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Pharmacy Department, Hospital Universitario y Politecnico La Fe, Valencia, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Infectious Disease Department, Hospital Universitario y Politecnico La Fe, Valencia, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Implantación de un programa de optimización de antimicrobianos en el paciente crítico: Estudio de intervención" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2017-05-26" "fechaAceptado" => "2017-07-14" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec989215" "palabras" => array:4 [ 0 => "Antimicrobial stewardship" 1 => "Antibiotics" 2 => "Antibiotic resistance" 3 => "Critical care" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec989216" "palabras" => array:4 [ 0 => "Antimicrobial stewardship" 1 => "Antibióticos" 2 => "Resistencia bacteriana" 3 => "Paciente crítico" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hospital antimicrobial stewardship programmes have achieved savings and a more rational use of antimicrobial treatments in general wards. The purpose of this report is to evaluate the experience of an antimicrobial stewardship programme in an intensive care unit (ICU).</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Design</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Prospective interventional, before-and-after study.</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Scope</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">24-bed medical ICU in a tertiary hospital.</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Intervention</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Prospective audit and feedback antimicrobial stewardship programme.</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Endpoints</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Antimicrobial consumption, antimicrobial related costs, multi-drug resistant microorganisms (MDRM) prevalence, nosocomial infections incidence, ICU length of stay, and ICU mortality rates were compared before and after one-year intervention.</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Results</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A total of 218 antimicrobial episodes of 182 patients were evaluated in 61 team meetings. Antimicrobial stewardship suggestions were accepted in 91.5% of the cases. Total antimicrobial DDD/100 patient-days consumption was reduced from 380.6 to 295.2 (-22.4%; p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0.037). Antimicrobial stewardship programme was associated with a significant decrease in the prescription of penicillins plus b-lactamase inhibitors, linezolid, cephalosporins, and aminoglycosides. Overall antimicrobial spending was reduced by €119,636. MDRM isolation and nosocomial infections per 100 patient-days did not change after the intervention period. No changes in length of stay or mortality rate were observed.</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusions</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">An ICU antimicrobial stewardship programme significantly reduced antimicrobial use without affecting inpatient mortality and length of stay. Our results further support the implementation of an antimicrobial stewardship programme in critical care units.</p></span>" "secciones" => array:7 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Objective" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Design" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Scope" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Intervention" ] 4 => array:2 [ "identificador" => "abst0025" "titulo" => "Endpoints" ] 5 => array:2 [ "identificador" => "abst0030" "titulo" => "Results" ] 6 => array:2 [ "identificador" => "abst0035" "titulo" => "Conclusions" ] ] ] "es" => array:3 [ "titulo" => "Resumen" "resumen" => "<span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Objetivo</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Los programas de optimización de antimicrobianos (PROA) han demostrado ser herramientas eficaces para reducir el uso de antimicrobianos. El propósito de este estudio es evaluar el efecto de la implantación de un PROA en una unidad de cuidados intensivos (UCI).</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Diseño</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Estudio prospectivo de intervención.</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Ámbito</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">UCI de 24 camas en un hospital terciario.</p></span> <span id="abst0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Intervención</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Implantación de un PROA basado en auditorías prospectivas.</p></span> <span id="abst0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Variables de interés principales</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">El consumo de antimicrobianos y sus los costes, la prevalencia de colonización por bacterias multi-resistentes (BMR), la incidencia de infección nosocomial, la estancia en UCI y las tasas de mortalidad fueron comparadas antes y tras un año de implantación del programa.</p></span> <span id="abst0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Se evaluaron un total de 218 episodios antimicrobianos de 182 pacientes en 61 reuniones. Él 91,5% de las sugerencias dadas por el equipo PROA fueron aceptadas por el prescriptor. El consumo total de antimicrobianos en DDD/100 estancias se redujo de 380,6 a 295,2 (-22,4%, p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0,037). La implantación del PROA se asoció con una disminución significativa en la prescripción de penicilinas/inhibidores de b-lactamasa, linezolid, cefalosporinas y aminoglucósidos. El gasto total en antimicrobianos se redujo en 119.636 €. La incidencia de colonización por BMR y de infecciones nosocomiales no cambiaron tras del período de intervención. No se observaron cambios en la duración de la estancia ni en la tasa de mortalidad.</p></span> <span id="abst0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Conclusiones</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">La implantación de un PROA en una UCI reduce significativamente el uso de antimicrobianos sin afectar a la evolución de los pacientes ingresados. Nuestros resultados apoyan la implementación de este tipo de programas en las unidades de pacientes críticos.</p></span>" "secciones" => array:7 [ 0 => array:2 [ "identificador" => "abst0040" "titulo" => "Objetivo" ] 1 => array:2 [ "identificador" => "abst0045" "titulo" => "Diseño" ] 2 => array:2 [ "identificador" => "abst0050" "titulo" => "Ámbito" ] 3 => array:2 [ "identificador" => "abst0055" "titulo" => "Intervención" ] 4 => array:2 [ "identificador" => "abst0060" "titulo" => "Variables de interés principales" ] 5 => array:2 [ "identificador" => "abst0065" "titulo" => "Resultados" ] 6 => array:2 [ "identificador" => "abst0070" "titulo" => "Conclusiones" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Ruiz J, Ramirez P, Gordon M, Villarreal E, Frasquet J, Poveda-Andres JL, et al. Implantación de un programa de optimización de antimicrobianos en el paciente crítico: Estudio de intervención. Med Intensiva. 2018;42:266–273.</p>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="sect0095">Further reading</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:1 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "[1]" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Ruiz J, Ramirez P, Gordon M, Villarreal E, Frasquet J, Poveda-Andres JL, Salavert-Lletí M, Catellanos A, Antimicrobial stewardship programme in critical care medicine: A prospective interventional study, <span class="elsevierStyleItalic">Medicina Intensiva (English Edition)</span>, doi: 10.1016/j.medine.2017.07.004" ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735727/0000004200000005/v1_201805310404/S2173572718301024/v1_201805310404/en/main.assets" "Apartado" => array:4 [ "identificador" => "411" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original articles" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735727/0000004200000005/v1_201805310404/S2173572718301024/v1_201805310404/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572718301024?idApp=WMIE" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 October | 20 | 21 | 41 |
2024 September | 37 | 44 | 81 |
2024 August | 39 | 50 | 89 |
2024 July | 32 | 42 | 74 |
2024 June | 47 | 52 | 99 |
2024 May | 32 | 33 | 65 |
2024 April | 42 | 44 | 86 |
2024 March | 30 | 55 | 85 |
2024 February | 28 | 47 | 75 |
2024 January | 26 | 46 | 72 |
2023 December | 21 | 43 | 64 |
2023 November | 30 | 52 | 82 |
2023 October | 24 | 37 | 61 |
2023 September | 22 | 42 | 64 |
2023 August | 18 | 24 | 42 |
2023 July | 25 | 35 | 60 |
2023 June | 22 | 15 | 37 |
2023 May | 34 | 30 | 64 |
2023 April | 20 | 23 | 43 |
2023 March | 27 | 47 | 74 |
2023 February | 23 | 37 | 60 |
2023 January | 18 | 29 | 47 |
2022 December | 30 | 44 | 74 |
2022 November | 39 | 39 | 78 |
2022 October | 34 | 44 | 78 |
2022 September | 29 | 44 | 73 |
2022 August | 33 | 38 | 71 |
2022 July | 24 | 40 | 64 |
2022 June | 21 | 34 | 55 |
2022 May | 20 | 48 | 68 |
2022 April | 34 | 60 | 94 |
2022 March | 38 | 67 | 105 |
2022 February | 21 | 44 | 65 |
2022 January | 19 | 45 | 64 |
2021 December | 30 | 50 | 80 |
2021 November | 25 | 54 | 79 |
2021 October | 36 | 86 | 122 |
2021 September | 23 | 46 | 69 |
2021 August | 27 | 49 | 76 |
2021 July | 30 | 35 | 65 |
2021 June | 26 | 30 | 56 |
2021 May | 35 | 55 | 90 |
2021 April | 84 | 72 | 156 |
2021 March | 41 | 29 | 70 |
2021 February | 35 | 25 | 60 |
2021 January | 31 | 35 | 66 |
2020 December | 37 | 19 | 56 |
2020 November | 20 | 18 | 38 |
2020 October | 27 | 27 | 54 |
2020 September | 21 | 40 | 61 |
2020 August | 19 | 23 | 42 |
2020 July | 15 | 18 | 33 |
2020 June | 16 | 19 | 35 |
2020 May | 15 | 20 | 35 |
2020 April | 20 | 19 | 39 |
2020 March | 15 | 16 | 31 |
2020 February | 28 | 33 | 61 |
2020 January | 15 | 26 | 41 |
2019 December | 27 | 32 | 59 |
2019 November | 24 | 27 | 51 |
2019 October | 20 | 18 | 38 |
2019 September | 21 | 22 | 43 |
2019 August | 31 | 20 | 51 |
2019 July | 27 | 26 | 53 |
2019 June | 16 | 17 | 33 |
2019 May | 39 | 37 | 76 |
2019 April | 13 | 18 | 31 |
2019 March | 11 | 25 | 36 |
2019 February | 17 | 30 | 47 |
2019 January | 13 | 40 | 53 |
2018 December | 13 | 31 | 44 |
2018 November | 72 | 31 | 103 |
2018 October | 8 | 9 | 17 |
2018 July | 0 | 2 | 2 |
2018 June | 0 | 3 | 3 |