Letter to the Editor
Materials engineering, mechanical power, protective ventilation and a parachute
Ingeniería de materiales, mechanical power, ventilación protectora y una de paracaídas
P. Escudero-Acha, A. González-Castro
, Y. Peñasco, M. Feo-Gonzalez
Corresponding author
Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
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Groups were compared by the log rank test (Mantel–Henzel). Circulating Lymphocyte Count (CLC) at HAS diagnosis were divided in two groups, ≤775<span class="elsevierStyleHsp" style=""></span>lymphocytes/mm<span class="elsevierStyleSup">3</span> and greater. Time was censored at 90 days following HAS diagnosis. Cum: cumulative.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "C. López-Mestanza, D. Andaluz-Ojeda, J.R. Gómez-López, J.F. Bermejo-Martín" "autores" => array:4 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "López-Mestanza" ] 1 => array:2 [ "nombre" => "D." "apellidos" => "Andaluz-Ojeda" ] 2 => array:2 [ "nombre" => "J.R." "apellidos" => "Gómez-López" ] 3 => array:2 [ "nombre" => "J.F." "apellidos" => "Bermejo-Martín" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572719301845?idApp=WMIE" "url" => "/21735727/0000004300000008/v1_201910261026/S2173572719301845/v1_201910261026/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Materials engineering, mechanical power, protective ventilation and a parachute" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "513" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "P. Escudero-Acha, A. González-Castro, Y. Peñasco, M. Feo-Gonzalez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Escudero-Acha" ] 1 => array:4 [ "nombre" => "A." "apellidos" => "González-Castro" "email" => array:1 [ 0 => "e409@humv.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "Y." "apellidos" => "Peñasco" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Feo-Gonzalez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Ingeniería de materiales, <span class="elsevierStyleItalic">mechanical power,</span> ventilación protectora y una de paracaídas" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have been carefully and enthusiastically reading the manuscript written by Modesto et al. published in your journal.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Citing the authors: the fact of interpreting the existence of a mechanical power (MP) threshold that would be originating ventilator-induced lung injury (VILI) means undoubtfully that what we are talking about here is the future of mechanical ventilation.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> However, paradigm shifts are never easy.</p><p id="par0015" class="elsevierStylePara elsevierViewall">This storm of new concepts, at least for the undersigned, opens a new path in our passion for mechanical ventilation. However, before jumping into opening new doors maybe we should reflect on whether we have managed to close old doors. Is the protective mechanical ventilation completely integrated today in our daily practice for the management of respiratory distress?<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> Some will be shocked to know that the answer is “no”.</p><p id="par0020" class="elsevierStylePara elsevierViewall">We will be a little more controversial. The escalation of respiratory support measures is happening arbitrarily and triggered by the actual technological trends. The so-called extracorporeal membrane oxygenation (ECMO) technique is the next best thing today.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The statement “ECMO saves lives”<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> will need to be confirmed in the future. For the time being it is established that protective ventilation saves lives, muscle relaxation saves lives and prone ventilation saves lives in the management of distress. Let's do a fly-by on the tools we have available today.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Nearly 15 years ago now, the authors of a very clever paper concluded that the effectiveness of parachutes had not been put to rigorous test through randomized controlled clinical trials. They also claimed that everybody would benefit here if the most radical detractors put together a blinded, randomized, placebo-controlled clinical trial on the use of parachutes.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Maybe the time is ripe now. If possible and feasible, let's find the funding for such a trial and let's coordinate it.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> Let us look for the volunteers of this trial among those in whom technological trends take over the rational use of our tools: “Rational escalation of ventilatory support measures that have proven successful increasing survival” versus “the machine that is in fashion now comes first”.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Escudero-Acha P, González-Castro A, Peñasco Y, Feo-Gonzalez M. Ingeniería de materiales, <span class="elsevierStyleItalic">mechanical power,</span> ventilación protectora y una de paracaídas. Med Intensiva. 2019;43:513.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0030" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical implications of the rheological theory in the prevention of ventilator-induced lung injury: is mechanical power the solution?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I. Modesto" 1 => "V. Alapont" 2 => "M. Aguar Carrascosa" 3 => "A. Medina Villanueva" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.medin.2018.06.005" "Revista" => array:2 [ "tituloSerie" => "Med Intensiva" "fecha" => "2018" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0035" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "ESICM Trials Group" "etal" => true "autores" => array:6 [ 0 => "G. Bellani" 1 => "J.G. Laffey" 2 => "T. Pham" 3 => "E. Fan" 4 => "L. Brochard" 5 => "A. 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Pell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/bmj.327.7429.1459" "Revista" => array:6 [ "tituloSerie" => "BMJ" "fecha" => "2003" "volumen" => "327" "paginaInicial" => "1459" "paginaFinal" => "1461" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14684649" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0050" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Use of ECMO in ARDS: does the EOLIA trial really help?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Gattinoni" 1 => "F. Vasques" 2 => "M. Quintel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/s13054-018-2098-6" "Revista" => array:5 [ "tituloSerie" => "Crit Care" "fecha" => "2018" "volumen" => "22" "paginaInicial" => "171" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29976250" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735727/0000004300000008/v1_201910261026/S2173572719301456/v1_201910261026/en/main.assets" "Apartado" => array:4 [ "identificador" => "64604" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735727/0000004300000008/v1_201910261026/S2173572719301456/v1_201910261026/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572719301456?idApp=WMIE" ]
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