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Higuera Lucas, A. Blandino Ortíz, C. Soriano Cuesta, R. de Pablo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Higuera Lucas" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Blandino Ortíz" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Soriano Cuesta" ] 3 => array:2 [ "nombre" => "R." "apellidos" => "de Pablo" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572722001291?idApp=WMIE" "url" => "/21735727/0000004600000007/v1_202206240715/S2173572722001291/v1_202206240715/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S217357272200128X" "issn" => "21735727" "doi" => "10.1016/j.medine.2021.10.012" "estado" => "S300" "fechaPublicacion" => "2022-07-01" "aid" => "1713" "copyright" => "Elsevier España, S.L.U. and SEMICYUC" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Med Intensiva. 2022;46:410-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific letter</span>" "titulo" => "Heterogeneity of hypoxemia severity according to pulse oximetry and blood gas analysis in COVID-19 pneumonia" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "410" "paginaFinal" => "412" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Heterogeneidad de la severidad de hipoxemia de acuerdo a oximetría de pulso y gases arteriales en neumonía COVID-19" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1003 "Ancho" => 2917 "Tamanyo" => 274800 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Correlation between oxygenation indexes. SpO<span class="elsevierStyleInf">2</span>: oxygen saturation with pulse oximeter; PaO<span class="elsevierStyleInf">2</span>: oxygen pressure in arterial blood; SatO<span class="elsevierStyleInf">2</span>: oxygen saturation in arterial blood; FiO<span class="elsevierStyleInf">2</span>: fraction of inspired oxygen.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I. Núñez, A. Soto-Mota" "autores" => array:2 [ 0 => array:2 [ "nombre" => "I." "apellidos" => "Núñez" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Soto-Mota" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357272200128X?idApp=WMIE" "url" => "/21735727/0000004600000007/v1_202206240715/S217357272200128X/v1_202206240715/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Use of the ROX index in the assessment of success of high-flow oxygen therapy in secondary hypoxemia to type 2 coronavirus" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "413" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. González-Castro, A. Fajardo Campoverde, A. Roncalli Rocha" "autores" => array:4 [ 0 => array:3 [ "nombre" => "A." "apellidos" => "González-Castro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "A." "apellidos" => "Fajardo Campoverde" "email" => array:1 [ 0 => "drauriopiotr@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Roncalli Rocha" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:1 [ "colaborador" => "Grupo LATAM de ventilación mecánica (WeVent)" ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna – Unidad de Paciente Crítico, Viña del Mar, Chile" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Hospital Escola Helvio Auto Maceió, Maceió, Brazil" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Utilización del índice de ROX en la valoración del éxito de oxigenoterapia de alto flujo en la hipoxemia secundaria a coronavirus tipo 2" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">High-flow nasal cannula (HFNC) provide high-flow oxygen—up to 60 L/min—with FiO<span class="elsevierStyleInf">2</span> between 0.21 and 1. The potential benefits would be: improved respiratory pattern with a lower respiratory rate (RR).</p><p id="par0010" class="elsevierStylePara elsevierViewall">One variable suggested to assess success or failure is the ROX index (ROXI) that combines oxygenation (SpO<span class="elsevierStyleInf">2</span>/FiO<span class="elsevierStyleInf">2</span> ratio) and respiratory effort (RE). Its validity in the management of COVID-19-related pneumonia has a high sensitivity to predict failed therapies,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> and is associated with a high mortality rate (45.4%).<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Regarding the denominator (RE) in the assessment of the ROXI, the retrograde, transcriptional, and hematogenous neuronal dissemination have been reported as possible access routes used by SARS-CoV-2 to enter the central nervous system. As a matter of fact, respiratory and cardiovascular vital centers of the brainstem are potential targets for SARS-CoV-2.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Sensitivity changes to peripheral chemoreceptors of carotid bodies invaded by SARS-CoV-2 can lead to a disproportionate ventilatory response at hypoxia level. Hyperexcitability can be developed in some cases and desensitization in others. Therefore, changes to the RE during the use of HFNC may not be associated directly with respiratory effort.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">During atypical acute respiratory distress syndrome (ARDS) due to SARS-CoV-2, patients often show a relatively well-preserved pulmonary mechanism that is not consistent with the severity of hypoxemia. To this point, several mechanisms converge: dysregulated pulmonary perfusion and hypoxic vasoconstriction, “infectious toxic encephalopathy” (central hypoxia), and damage to the carotid body<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> that could also be a route of infection into the nervous system.</p><p id="par0025" class="elsevierStylePara elsevierViewall">We believe that we should be cautious when using the ROX index only as a predictor of success or failure in these patients.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0030" class="elsevierStylePara elsevierViewall">None reported.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">None whatsoever.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: González-Castro A, Fajardo Campoverde A, Roncalli Rocha A, Grupo LATAM de ventilación mecánica (WeVent). Utilización del índice de ROX en la valoración del éxito de oxigenoterapia de alto flujo en la hipoxemia secundaria a coronavirus tipo 2. Med Intensiva. 2022;46:413.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Validity of ROX index in prediction of risk of intubation in patients with COVID-19 pneumonia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L. Suliman" 1 => "T. Abdelgawad" 2 => "N. Farrag" 3 => "H. Abdelwahab" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5603/ARM.a2020.0176" "Revista" => array:6 [ "tituloSerie" => "Adv Respir Med" "fecha" => "2021" "volumen" => "89" "paginaInicial" => "1" "paginaFinal" => "7" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33471350" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High-flow nasal cannula in COVID-19: outcomes of application and examination of the ROX index to predict success" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Chandel" 1 => "S. Patolia" 2 => "A.W. Brown" 3 => "A.C. Collins" 4 => "D. Sahjwani" 5 => "V. Khangoora" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4187/respcare.08631" "Revista" => array:6 [ "tituloSerie" => "Respir Care" "fecha" => "2020" "volumen" => "66" "paginaInicial" => "909" "paginaFinal" => "919" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33328179" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Y. Li" 1 => "W. Bai" 2 => "T. Hashikawa" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jmv.25728" "Revista" => array:6 [ "tituloSerie" => "J Med Virol" "fecha" => "2020" "volumen" => "92" "paginaInicial" => "552" "paginaFinal" => "555" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32104915" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relevance of carotid bodies in COVID-19: a hypothetical viewpoint" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "B. Machado" 1 => "J. Paton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Auton Neurosci" "fecha" => "2021" "volumen" => "233" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "SARS-CoV-2 in carotid body" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "B. Lambermont" 1 => "E. Davenne" 2 => "F. Maclot" 3 => "P. Delvenne" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00134-021-06351-z" "Revista" => array:6 [ "tituloSerie" => "Intensive Care Med" "fecha" => "2021" "volumen" => "47" "paginaInicial" => "342" "paginaFinal" => "343" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33481041" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735727/0000004600000007/v1_202206240715/S2173572722000832/v1_202206240715/en/main.assets" "Apartado" => array:4 [ "identificador" => "64604" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735727/0000004600000007/v1_202206240715/S2173572722000832/v1_202206240715/en/main.pdf?idApp=WMIE&text.app=https://medintensiva.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173572722000832?idApp=WMIE" ]
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