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Images in Intensive Medicine
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Available online 26 August 2025
A rare complication of Bordetella pertussis infection
Una complicación rara de la infección por Bordetella pertussis
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Carolina V. Monteiroa,b,
Corresponding author
, Paulo Martins Fernandesc, João Lourinhod,e
a Serviço de Infeciologia, Unidade Local de Saúde de São João, Hospital de São João, 4200-319, Porto, Portugal
b Faculdade de Medicina, Universidade do Porto, 4200-319, Porto, Portugal
c Serviço de Medicina Intensiva, Unidade Local de Saúde do Baixo Alentejo, Hospital José Joaquim Fernandes, 7801-849, Beja, Portugal
d Serviço de Infeciologia, Unidade Local de Saúde de Almada-Seixal, Hospital Garcia de Orta, 2805-267, Almada, Portugal
e Universidade de Lisboa, Faculdade de Medicina, Clínica Universitária de Doenças Infeciosas, 1649-028, Lisboa, Portugal
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A 65-year-old man was admitted with a two-week history of dry cough, coughing fits and worsening left thoracic pain. He showed respiratory failure and subcutaneous emphysema of the face, neck, and chest. CT scan (Fig. 1A and B) revealed subcutaneous emphysema, pneumomediastinum, left pneumothorax, and parietal pleura detachment. Despite high-flow oxygen (FiO2 100%), PaO2/FiO2 dropped from 391 to 97 in two days, and emphysema extended to the abdomen and groin. Veno-venous extracorporeal membrane oxygenation (VV-ECMO) was initiated to avoid intubation due to a suspected bronchotracheal leak. Polymerase chain reaction (PCR) for Bordetella pertussis was positive, and azithromycin was started. The patient recovered fully after five days on VV-ECMO. Given the current global whooping cough outbreak, B. pertussis should be considered in adults with compatible symptoms.

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CRediT authorship contribution statement

All authors contributed to conceptualization, methodology, writing, review and edition of this article. All authors discussed the results and contributed to the final manuscript. All authors have read and agreed to the published version of the manuscript.

Fundings

This research received no external funding.

Declaration of competing interest

The authors declare no conflicts of interest.

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